| Rank | Movie Title (click to view) | Studio | Gross / Theaters | Total Gross / % of Total | Open |
| 1 | Harry Potter and the Deathly Hallows Part 2 | WB | $381,011,219 | 4,375 | $381,011,219 | 100.0% | 7/15/11 |
| 2 | The Hangover Part II | WB | $254,464,305 | 3,675 | $254,464,305 | 100.0% | 5/26/11 |
| 3 | Sherlock Holmes: A Game of Shadows | WB | $124,051,629 | 3,703 | $186,848,418 | 66.4% | 12/16/11 |
| 4 | Horrible Bosses | WB (NL) | $117,538,559 | 3,134 | $117,538,559 | 100.0% | 7/8/11 |
| 5 | Green Lantern | WB | $116,601,172 | 3,816 | $116,601,172 | 100.0% | 6/17/11 |
| 6 | Crazy, Stupid, Love. | WB | $84,351,197 | 3,020 | $84,351,197 | 100.0% | 7/29/11 |
| 7 | Contagion | WB | $75,658,097 | 3,222 | $75,658,097 | 100.0% | 9/9/11 |
| 8 | Dolphin Tale | WB | $71,922,716 | 3,515 | $72,286,779 | 99.5% | 9/23/11 |
| 9 | Unknown | WB | $63,686,397 | 3,043 | $63,686,397 | 100.0% | 2/18/11 |
| 10 | Happy Feet Two | WB | $60,692,394 | 3,611 | $64,006,466 | 94.8% | 11/18/11 |
| 11 | Hall Pass | WB (NL) | $45,060,734 | 2,950 | $45,060,734 | 100.0% | 2/25/11 |
| 12 | New Year's Eve | WB (NL) | $44,205,254 | 3,505 | $54,544,638 | 81.0% | 12/9/11 |
| 13 | Yogi Bear | WB | $42,827,461 | 3,515 | $100,246,011 | 42.7% | 12/17/10 |
| 14 | Final Destination 5 | WB (NL) | $42,587,643 | 3,155 | $42,587,643 | 100.0% | 8/12/11 |
| 15 | Something Borrowed | WB | $39,046,489 | 2,904 | $39,046,489 | 100.0% | 5/6/11 |
| 16 | Red Riding Hood | WB | $37,662,162 | 3,030 | $37,662,162 | 100.0% | 3/11/11 |
| 17 | J. Edgar | WB | $36,493,051 | 1,985 | $37,306,030 | 97.8% | 11/9/11 |
| 18 | Sucker Punch | WB | $36,392,502 | 3,033 | $36,392,502 | 100.0% | 3/25/11 |
| 19 | A Very Harold & Kumar 3D Christmas | WB (NL) | $34,853,056 | 2,875 | $35,061,031 | 99.4% | 11/4/11 |
| 20 | The Rite | WB (NL) | $33,047,633 | 2,985 | $33,047,633 | 100.0% | 1/28/11 |
| 21 | Arthur (2011) | WB | $33,035,397 | 3,276 | $33,035,397 | 100.0% | 4/8/11 |
| 22 | Harry Potter and the Deathly Hallows Part 1 | WB | $15,753,178 | 1,732 | $295,983,305 | 5.3% | 11/19/10 |
| 23 | Born to Be Wild (IMAX) | WB | $15,134,212 | 208 | $22,635,603 | 66.9% | 4/8/11 |
| 24 | Hubble 3D | WB | $10,059,349 | 50 | $37,733,996 | 26.7% | 3/19/10 |
| 25 | Under the Sea 3D | WB | $3,631,196 | 21 | $31,516,429 | 11.5% | 2/13/09 |
| 26 | Due Date | WB | $1,604,004 | 404 | $100,539,043 | 1.6% | 11/5/10 |
| 27 | The Lord of the Rings: The Return of the King (2011 re-release) | WB | $818,580 | 521 | $818,580 | 100.0% | 6/28/11 |
| 28 | The Lord of the Rings: The Fellowship of the Ring (2011 re-release) | WB | $768,580 | 522 | $768,580 | 100.0% | 6/14/11 |
| 29 | The Lord of the Rings: The Two Towers (2011 re-release) | WB | $764,607 | 522 | $764,607 | 100.0% | 6/21/11 |
| 30 | The Polar Express (2011 re-issue) | WB | $704,882 | 25 | $711,168 | 99.1% | 11/25/11 |
| 31 | Life as We Know It | WB | $647,338 | 248 | $53,374,681 | 1.2% | 10/8/10 |
| 32 | Deep Sea 3D (IMAX) | WB | $516,568 | 4 | $45,562,927 | 1.1% | 3/3/06 |
| 33 | Extremely Loud & Incredibly Close | WB | $267,923 | 6 | $31,847,881 | 0.8% | 12/25/11 |
| 34 | Legend of the Guardians: The Owls of Ga'Hoole | WB | $188,900 | 158 | $55,675,313 | 0.3% | 9/24/10 |
| 35 | Hereafter | WB | $62,486 | 128 | $32,746,941 | 0.2% | 10/15/10 |
| 36 | The Town | WB | $31,225 | 62 | $92,186,262 | 0.0% | 9/17/10 |
| 37 | Inception | WB | $18,007 | 28 | $292,576,195 | 0.0% | 7/16/10 |
| 38 | The Polar Express (IMAX re-issue 2010) | WB | $11,923 | 15 | $672,796 | 1.8% | 12/3/10 |
| Summary of 38 Movies on Chart: |
| Totals: | $1,826,172,025 | - | - | - | - |
| Averages: | $48,057,159 | - | - | - | - |
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