| Rank | Movie Title (click to view) | Studio | Total Gross / Theaters | Opening / Theaters | Open |
| 1 | E.T.: The Extra-Terrestrial | Uni. | $359,197,037 | 1,778 | $11,835,389 | 1,103 | 6/11/82 |
| 2 | Jurassic Park | Uni. | $357,067,947 | 2,566 | $47,026,828 | 2,404 | 6/11/93 |
| 3 | Meet the Fockers | Uni. | $279,261,160 | 3,554 | $46,120,980 | 3,518 | 12/22/04 |
| 4 | How the Grinch Stole Christmas | Uni. | $260,044,825 | 3,256 | $55,082,330 | 3,127 | 11/17/00 |
| 5 | Jaws | Uni. | $260,000,000 | 675 | $7,061,513 | 409 | 6/20/75 |
| 6 | Despicable Me | Uni. | $251,513,985 | 3,602 | $56,397,125 | 3,476 | 7/9/10 |
| 7 | Bruce Almighty | Uni. | $242,829,261 | 3,549 | $67,953,330 | 3,483 | 5/23/03 |
| 8 | The Lost World: Jurassic Park | Uni. | $229,086,679 | 3,565 | $72,132,785 | 3,281 | 5/23/97 |
| 9 | The Bourne Ultimatum | Uni. | $227,471,070 | 3,701 | $69,283,690 | 3,660 | 8/3/07 |
| 10 | Ted | Uni. | $218,815,487 | 3,303 | $54,415,205 | 3,239 | 6/29/12 |
| 11 | King Kong | Uni. | $218,080,025 | 3,627 | $50,130,145 | 3,568 | 12/14/05 |
| 12 | Dr. Seuss' The Lorax | Uni. | $214,030,500 | 3,769 | $70,217,070 | 3,729 | 3/2/12 |
| 13 | Back to the Future | Uni. | $210,609,762 | 1,550 | $11,152,500 | 1,420 | 7/3/85 |
| 14 | Fast Five | Uni. | $209,837,675 | 3,793 | $86,198,765 | 3,644 | 4/29/11 |
| 15 | The Mummy Returns | Uni. | $202,019,785 | 3,553 | $68,139,035 | 3,401 | 5/4/01 |
| 16 | Liar Liar | Uni. | $181,410,615 | 2,909 | $31,423,025 | 2,845 | 3/21/97 |
| 17 | Jurassic Park III | Uni. | $181,171,875 | 3,462 | $50,771,645 | 3,434 | 7/18/01 |
| 18 | The Bourne Supremacy | Uni. | $176,241,941 | 3,304 | $52,521,865 | 3,165 | 7/23/04 |
| 19 | Apollo 13 | Uni. | $172,071,312 | 2,347 | $25,353,380 | 2,197 | 6/30/95 |
| 20 | A Beautiful Mind | Uni. | $170,742,341 | 2,250 | $367,151 | 11 | 12/21/01 |
| 21 | Bridesmaids | Uni. | $169,106,725 | 2,958 | $26,247,410 | 2,918 | 5/13/11 |
| 22 | Meet the Parents | Uni. | $166,244,045 | 2,697 | $28,623,300 | 2,614 | 10/6/00 |
| 23 | The Sting | Uni. | $156,000,000 | N/A | N/A | N/A | 12/25/73 |
| 24 | The Mummy | Uni. | $155,385,488 | 3,411 | $43,369,635 | 3,210 | 5/7/99 |
| 25 | Snow White and the Huntsman | Uni. | $155,332,381 | 3,777 | $56,217,700 | 3,773 | 6/1/12 |
| 26 | Fast and Furious | Uni. | $155,064,265 | 3,674 | $70,950,500 | 3,461 | 4/3/09 |
| 27 | Les Miserables (2012) | Uni. | $148,809,770 | 2,927 | $27,281,735 | 2,814 | 12/25/12 |
| 28 | Knocked Up | Uni. | $148,768,917 | 2,975 | $30,690,990 | 2,871 | 6/1/07 |
| 29 | Little Fockers | Uni. | $148,438,600 | 3,675 | $30,833,665 | 3,536 | 12/22/10 |
| 30 | American Pie 2 | Uni. | $145,103,595 | 3,157 | $45,117,985 | 3,063 | 8/10/01 |
| 31 | The Fast and the Furious | Uni. | $144,533,925 | 2,899 | $40,089,015 | 2,628 | 6/22/01 |
| 32 | Mamma Mia! | Uni. | $144,130,063 | 3,194 | $27,751,240 | 2,976 | 7/18/08 |
| 33 | Patch Adams | Uni. | $135,026,902 | 2,909 | $25,262,280 | 2,712 | 12/25/98 |
| 34 | The Incredible Hulk | Uni. | $134,806,913 | 3,508 | $55,414,050 | 3,505 | 6/13/08 |
| 35 | Wanted | Uni. | $134,508,551 | 3,185 | $50,927,085 | 3,175 | 6/27/08 |
| 36 | Identity Thief | Uni. | $134,049,465 | 3,230 | $34,551,025 | 3,141 | 2/8/13 |
| 37 | Hulk | Uni. | $132,177,234 | 3,674 | $62,128,420 | 3,660 | 6/20/03 |
| 38 | The Flintstones | Uni. | $130,531,208 | 2,594 | $29,688,730 | 2,498 | 5/27/94 |
| 39 | American Gangster | Uni. | $130,164,645 | 3,110 | $43,565,115 | 3,054 | 11/2/07 |
| 40 | The Nutty Professor (1996) | Uni. | $128,814,019 | 2,239 | $25,411,725 | 2,115 | 6/28/96 |
| 41 | 2 Fast 2 Furious | Uni. | $127,154,901 | 3,418 | $50,472,480 | 3,408 | 6/6/03 |
| 42 | Smokey and the Bandit | Uni. | $126,737,428 | N/A | N/A | N/A | 5/27/77 |
| 43 | Safe House | Uni. | $126,373,434 | 3,121 | $40,172,720 | 3,119 | 2/10/12 |
| 44 | Erin Brockovich | Uni. | $125,595,205 | 3,070 | $28,138,465 | 2,848 | 3/17/00 |
| 45 | The Nutty Professor II: The Klumps | Uni. | $123,309,890 | 3,251 | $42,518,830 | 3,242 | 7/28/00 |
| 46 | The Bourne Identity | Uni. | $121,661,683 | 2,663 | $27,118,640 | 2,638 | 6/14/02 |
| 47 | Seabiscuit | Uni. | $120,277,854 | 2,573 | $20,854,735 | 1,989 | 7/25/03 |
| 48 | Van Helsing | Uni. | $120,177,084 | 3,580 | $51,748,040 | 3,575 | 5/7/04 |
| 49 | National Lampoon's Animal House | Uni. | $120,091,123 | N/A | $276,538 | 12 | 7/28/78 |
| 50 | I Now Pronounce You Chuck and Larry | Uni. | $120,059,556 | 3,501 | $34,233,750 | 3,495 | 7/20/07 |
| 51 | On Golden Pond | Uni. | $119,285,432 | 1,015 | $89,213 | 2 | 12/4/81 |
| 52 | The Break-Up | Uni. | $118,703,275 | 3,146 | $39,172,785 | 3,070 | 6/2/06 |
| 53 | Back to the Future Part II | Uni. | $118,450,002 | 2,107 | $27,835,125 | 1,865 | 11/22/89 |
| 54 | 8 Mile | Uni. | $116,750,901 | 2,585 | $51,240,555 | 2,470 | 11/8/02 |
| 55 | Notting Hill | Uni. | $116,089,678 | 2,786 | $21,811,180 | 2,747 | 5/28/99 |
| 56 | American Graffiti | Uni. | $115,000,000 | N/A | N/A | N/A | 8/1/73 |
| 57 | The Bourne Legacy | Uni. | $113,203,870 | 3,753 | $38,142,825 | 3,745 | 8/10/12 |
| 58 | It's Complicated | Uni. | $112,735,375 | 2,955 | $22,100,820 | 2,887 | 12/25/09 |
| 59 | Twins | Uni. | $111,938,388 | 1,659 | $11,174,980 | 1,396 | 12/9/88 |
| 60 | The 40-Year-Old Virgin | Uni. | $109,449,237 | 3,006 | $21,422,815 | 2,845 | 8/19/05 |
| 61 | Couples Retreat | Uni. | $109,204,945 | 3,074 | $34,286,740 | 3,000 | 10/9/09 |
| 62 | Hop | Uni. | $108,085,305 | 3,616 | $37,543,710 | 3,579 | 4/1/11 |
| 63 | Robin Hood | Uni. | $105,269,730 | 3,505 | $36,063,385 | 3,503 | 5/14/10 |
| 64 | American Wedding | Uni. | $104,565,114 | 3,175 | $33,369,440 | 3,172 | 8/1/03 |
| 65 | American Pie | Uni. | $102,561,004 | 2,544 | $18,709,680 | 2,508 | 7/9/99 |
| 66 | The Mummy: Tomb of the Dragon Emperor | Uni. | $102,491,776 | 3,778 | $40,457,770 | 3,760 | 8/1/08 |
| 67 | The Cat in the Hat | Uni. | $101,149,285 | 3,467 | $38,329,160 | 3,464 | 11/21/03 |
| 68 | Airport | Uni. | $100,489,151 | N/A | N/A | N/A | 3/5/70 |
| 69 | Evan Almighty | Uni. | $100,462,298 | 3,636 | $31,192,615 | 3,604 | 6/22/07 |
| 70 | Casper | Uni. | $100,328,194 | 2,757 | $16,840,385 | 2,714 | 5/26/95 |
| 71 | Cowboys & Aliens | Uni. | $100,240,551 | 3,754 | $36,431,290 | 3,750 | 7/29/11 |
| 72 | Parenthood | Uni. | $100,047,830 | 1,399 | $10,506,450 | 1,262 | 8/2/89 |
| 73 | Public Enemies | Uni. | $97,104,620 | 3,336 | $25,271,675 | 3,334 | 7/1/09 |
| 74 | Schindler's List | Uni. | $96,065,768 | 1,389 | $656,636 | 25 | 12/15/93 |
| 75 | Red Dragon | Uni. | $93,149,898 | 3,363 | $36,540,945 | 3,357 | 10/4/02 |
| 76 | Kindergarten Cop | Uni. | $91,457,688 | 1,937 | $7,918,560 | 1,833 | 12/22/90 |
| 77 | The Scorpion King | Uni. | $91,047,077 | 3,466 | $36,075,875 | 3,444 | 4/19/02 |
| 78 | Inside Man | Uni. | $88,513,495 | 2,867 | $28,954,945 | 2,818 | 3/24/06 |
| 79 | Waterworld | Uni. | $88,246,220 | 2,420 | $21,171,780 | 2,268 | 7/28/95 |
| 80 | Along Came Polly | Uni. | $88,097,164 | 3,052 | $27,721,185 | 2,984 | 1/16/04 |
| 81 | Back to the Future Part III | Uni. | $87,727,583 | 2,070 | $19,089,645 | 2,019 | 5/25/90 |
| 82 | Out of Africa | Uni. | $87,071,205 | 1,102 | $3,637,290 | 922 | 12/20/85 |
| 83 | Oblivion | Uni. | $86,685,000 | 3,792 | $37,054,485 | 3,783 | 4/19/13 |
| 84 | Brokeback Mountain | Focus | $83,043,761 | 2,089 | $547,425 | 5 | 12/9/05 |
| 85 | Fried Green Tomatoes | Uni. | $82,418,501 | 1,331 | $105,317 | 5 | 12/27/91 |
| 86 | Earthquake | Uni. | $79,666,653 | N/A | N/A | N/A | 11/15/74 |
| 87 | Cape Fear | Uni. | $79,091,969 | 1,707 | $10,261,025 | 924 | 11/15/91 |
| 88 | Tower Heist | Uni. | $78,046,570 | 3,870 | $24,025,190 | 3,367 | 11/4/11 |
| 89 | Backdraft | Uni. | $77,868,585 | 1,983 | $12,686,200 | 1,852 | 5/24/91 |
| 90 | Jaws 2 | Uni. | $77,737,272 | 640 | $9,866,023 | 640 | 6/16/78 |
| 91 | U-571 | Uni. | $77,122,415 | 2,820 | $19,553,310 | 2,583 | 4/21/00 |
| 92 | Hellboy II: The Golden Army | Uni. | $75,986,503 | 3,212 | $34,539,115 | 3,204 | 7/11/08 |
| 93 | The Family Man | Uni. | $75,793,305 | 2,441 | $10,554,960 | 2,388 | 12/22/00 |
| 94 | You, Me and Dupree | Uni. | $75,628,110 | 3,137 | $21,525,560 | 3,131 | 7/14/06 |
| 95 | Ray | Uni. | $75,331,600 | 2,474 | $20,039,730 | 2,006 | 10/29/04 |
| 96 | Coraline | Focus | $75,286,229 | 2,320 | $16,849,640 | 2,299 | 2/6/09 |
| 97 | The Jerk | Uni. | $73,691,419 | 525 | $5,935,025 | 525 | 12/14/79 |
| 98 | The Interpreter | Uni. | $72,708,161 | 2,814 | $22,822,455 | 2,758 | 4/22/05 |
| 99 | Mama | Uni. | $71,628,180 | 2,781 | $28,402,310 | 2,647 | 1/18/13 |
| 100 | Bird on a Wire | Uni. | $70,978,012 | 2,008 | $15,338,160 | 1,944 | 5/18/90 |
| Summary of 713 Movies on Chart: |
| Totals: | $26,862,830,556 | - | - | - | - |
| Averages: | $37,675,779 | - | - | - | - |
 |
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