| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Mr. & Mrs. Smith | $4,889,919 | - | - | - | - | $4,889,919 | 1 | 20th Century Fox International | true | false |
| 2 | 2 | The Longest Yard | $1,704,053 | -31.7% | - | - | - | $4,985,254 | 2 | Sony Pictures Releasing | false | false |
| 3 | 1 | Star Wars: Episode III - Revenge of the Sith | $1,634,644 | -38.5% | - | - | - | $23,441,889 | 4 | 20th Century Fox International | false | false |
| 4 | - | Madagascar | $1,485,420 | - | - | - | - | $1,675,924 | - | United International Pictures | - | false |
| 5 | 3 | A Lot Like Love | $188,903 | -43.7% | - | - | - | $656,603 | 2 | Buena Vista International | false | false |
| 6 | 4 | The Wedding Date | $155,644 | -45.1% | - | - | - | $1,211,813 | 3 | Roadshow Films | false | false |
| 7 | 5 | Coach Carter | $137,828 | -46.2% | - | - | - | $1,305,798 | 3 | United International Pictures | false | false |
| 8 | 8 | The Hitchhiker's Guide to the Galaxy | $137,402 | -29.3% | - | - | - | $6,613,715 | 7 | Buena Vista International | false | false |
| 9 | 6 | The Upside of Anger | $124,952 | -46.1% | - | - | - | $2,568,936 | 5 | Hoyts Distribution | false | false |
| 10 | 9 | Crash | $93,581 | -26% | - | - | - | $1,231,342 | 7 | Icon Film Distribution | false | false |
| 11 | 7 | Kingdom of Heaven | $91,092 | -55.8% | - | - | - | $6,262,849 | 6 | 20th Century Fox International | false | false |
| 12 | - | The Assassination of Richard Nixon | $67,537 | - | - | - | - | $77,706 | 1 | Dendy Films | true | false |
| 13 | - | Peaches | $61,585 | - | - | - | - | $74,843 | 1 | Hopscotch Films | true | false |
| 14 | 12 | Downfall | $56,882 | -16.1% | - | - | - | $1,380,078 | 8 | Hopscotch Films | false | false |
| 15 | 13 | Ladies in Lavender | $56,170 | -11.2% | - | - | - | $2,296,554 | 12 | Icon Film Distribution | false | false |
| 16 | 14 | Melinda and Melinda | $40,143 | -35.4% | - | - | - | $234,958 | 3 | 20th Century Fox International | false | false |
| 17 | 15 | The Machinist | $39,434 | -35.8% | - | - | - | $129,230 | 2 | Rialto Distribution | false | false |
| 18 | 20 | What the #$*! Do We (K)now!? 2005 Re-release | $39,150 | +1.2% | - | - | - | $584,776 | 9 | Hopscotch Films | false | false |
| 19 | 18 | Three Dollars | $36,648 | -18.6% | - | - | - | $872,846 | 8 | Dendy Films | false | false |
| 20 | 19 | 2046 | $34,459 | -21.7% | - | - | - | $182,411 | 3 | Hopscotch Films | false | false |
