| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Madagascar | $8,571,866 | - | 834 | - | $10,278 | $8,571,866 | 1 | United International Pictures | true | false |
| 2 | 1 | War of the Worlds | $1,524,993 | -59.5% | 845 | - | $1,804 | $15,982,210 | 3 | United International Pictures | false | false |
| 3 | - | Fantastic Four | $1,321,593 | - | 434 | - | $3,045 | $1,321,593 | 1 | Constantin Film | true | false |
| 4 | - | Wedding Crashers | $652,091 | - | 364 | - | $1,791 | $652,091 | 1 | Warner Bros. | true | false |
| 5 | 2 | Batman Begins | $183,930 | -73.2% | 410 | -264 | $448 | $6,315,852 | 5 | Warner Bros. | false | false |
| 6 | 3 | The Hitchhiker's Guide to the Galaxy | $173,322 | -70.9% | 402 | -143 | $431 | $7,272,672 | 6 | Buena Vista International | false | false |
| 7 | 4 | Star Wars: Episode III - Revenge of the Sith | $138,124 | -67.8% | 254 | -200 | $543 | $44,574,858 | 9 | 20th Century Fox International | false | false |
| 8 | 6 | Antibodies | $125,323 | -63.1% | 188 | -1 | $666 | $653,466 | 2 | Kinowelt Filmverleih | false | false |
| 9 | 8 | The Upside of Anger | $99,445 | -62.5% | 75 | +7 | $1,325 | $439,243 | 2 | TOBIS Film | false | false |
| 10 | 15 | Go for Zucker | $92,874 | +55.6% | 92 | +24 | $1,009 | $5,438,783 | 28 | X Verleih AG | false | false |
| 11 | 5 | A Lot Like Love | $72,652 | -80.4% | 245 | -16 | $296 | $1,622,116 | 4 | Buena Vista International | false | false |
| 12 | 7 | Monster-in-Law | $70,472 | -77.2% | 278 | -88 | $253 | $5,800,898 | 8 | Warner Bros. | false | false |
| 13 | 10 | Melinda and Melinda | $63,901 | -55.9% | 65 | +3 | $983 | $699,552 | 4 | 20th Century Fox International | false | false |
| 14 | - | Nicotina | $51,311 | - | 26 | - | $1,973 | $51,311 | 1 | Arsenal Filmverleih | true | false |
| 15 | 9 | Sahara | $42,390 | -82.6% | 191 | -199 | $221 | $4,548,253 | 7 | Universum Film (UFA) | false | false |
