| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Bewitched | $1,460,936 | <0.1% | 614 | +1 | $2,379 | $3,416,142 | 2 | Sony Pictures Releasing | false | false |
| 2 | 2 | Transporter 2 | $1,106,808 | -6% | 477 | +17 | $2,320 | $2,687,471 | 2 | Universum Film (UFA) | false | false |
| 3 | - | Red Eye | $950,153 | - | 347 | - | $2,738 | $950,153 | 1 | United International Pictures | true | false |
| 4 | - | Broken Flowers | $628,780 | - | 73 | - | $8,613 | $628,780 | 1 | TOBIS Film | true | false |
| 5 | 4 | The Skeleton Key | $471,803 | -19.5% | 297 | -3 | $1,588 | $4,809,942 | 4 | United International Pictures | false | false |
| 6 | - | Cinderella Man | $388,907 | - | 402 | - | $967 | $388,907 | 1 | Buena Vista International | true | false |
| 7 | 5 | Sin City | $370,565 | -24.8% | 453 | -30 | $818 | $8,200,854 | 5 | Buena Vista International | false | false |
| 8 | 3 | Land of the Dead | $337,860 | -49.7% | 197 | - | $1,715 | $1,197,140 | 2 | United International Pictures | false | false |
| 9 | 10 | Charlie and the Chocolate Factory | $337,679 | +24.4% | 479 | -7 | $704 | $5,298,941 | 5 | Warner Bros. | false | false |
| 10 | 9 | Madagascar | $333,049 | +19.7% | 672 | -79 | $495 | $42,329,886 | 9 | United International Pictures | false | false |
| 11 | 11 | Howl's Moving Castle | $307,758 | +14.1% | 412 | +5 | $746 | $1,243,365 | 3 | Universum Film (UFA) | false | false |
| 12 | 6 | Mr. & Mrs. Smith | $301,109 | -26.9% | 439 | -153 | $685 | $25,675,146 | 8 | Kinowelt Filmverleih | false | false |
| 13 | 7 | Must Love Dogs | $290,896 | -16.9% | 362 | +1 | $803 | $2,011,873 | 3 | Warner Bros. | false | false |
| 14 | 15 | Herbie Fully Loaded | $147,040 | +13.9% | 489 | -107 | $300 | $4,546,126 | 6 | Buena Vista International | false | false |
| 15 | 12 | Don't Come Knocking | $142,587 | -16% | 114 | - | $1,250 | $816,414 | 3 | United International Pictures | false | false |
