| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The 40-Year-Old Virgin | $1,220,774 | -24.1% | 256 | +13 | $4,768 | $3,430,225 | 2 | United International Pictures | false | false |
| 2 | - | In Her Shoes | $1,220,446 | - | 290 | - | $4,208 | $1,548,428 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Cinderella Man | $469,734 | -38.6% | 266 | -28 | $1,765 | $3,295,762 | 3 | Buena Vista International | false | false |
| 4 | 4 | Must Love Dogs | $379,708 | -48.3% | 177 | -1 | $2,145 | $1,387,338 | 2 | Warner Bros. | false | false |
| 5 | - | Pride & Prejudice | $355,572 | - | 176 | - | $2,020 | $355,572 | - | United International Pictures | - | false |
| 6 | 3 | Wallace & Gromit: The Curse of the Were-Rabbit | $341,680 | -53.7% | 236 | -28 | $1,447 | $7,368,223 | 5 | United International Pictures | false | false |
| 7 | - | Night Watch 2005 Re-release | $286,135 | - | 112 | - | $2,554 | $286,581 | 1 | 20th Century Fox International | true | false |
| 8 | 8 | The Dukes of Hazzard | $232,586 | -50.4% | 197 | -39 | $1,180 | $7,340,004 | 5 | Roadshow Films | false | false |
| 9 | 9 | Serenity | $229,527 | -45.3% | 161 | +44 | $1,425 | $1,966,258 | 3 | United International Pictures | false | false |
| 10 | 11 | The Proposition | $216,881 | -32.9% | 63 | - | $3,442 | $655,898 | 2 | Sony Pictures Releasing | false | false |
| 11 | 5 | Charlie and the Chocolate Factory | $198,681 | -65.2% | 229 | -44 | $867 | $18,160,771 | 7 | Roadshow Films | false | false |
| 12 | 7 | Sky High | $180,740 | -67.3% | 188 | -34 | $961 | $4,695,234 | 6 | Buena Vista International | false | false |
| 13 | 6 | The Adventures of Sharkboy and Lavagirl 3-D | $170,453 | -70% | 173 | -31 | $985 | $4,145,942 | 6 | Sony Pictures Releasing | false | false |
| 14 | 10 | Deuce Bigalow: European Gigolo | $151,499 | -55.3% | 176 | -26 | $860 | $3,876,527 | 4 | Sony Pictures Releasing | false | false |
| 15 | 13 | Transporter 2 | $117,318 | -52.7% | 102 | -32 | $1,150 | $1,222,492 | 3 | 20th Century Fox International | false | false |
| 16 | 14 | Little Fish | $110,987 | -37.7% | 61 | - | $1,819 | $2,040,439 | 6 | Icon Film Distribution | false | false |
| 17 | - | The Devil's Rejects | $93,041 | - | 65 | - | $1,431 | $93,041 | 1 | Hoyts Distribution | true | false |
| 18 | - | Enron: The Smartest Guys in the Room | $70,750 | - | 19 | - | $3,723 | $91,105 | 1 | Dendy Films | true | false |
| 19 | 18 | Look Both Ways | $43,727 | -17.5% | 45 | +6 | $971 | $1,703,082 | 9 | Dendy Films | false | false |
| 20 | 16 | Mad Hot Ballroom | $35,626 | -46.4% | 33 | - | $1,079 | $253,125 | 3 | Icon Film Distribution | false | false |
