| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Inside Man | $1,346,609 | - | 228 | - | $5,906 | $1,739,238 | 1 | United International Pictures | true | false |
| 2 | - | V for Vendetta | $1,187,167 | - | 202 | - | $5,877 | $1,188,000 | 1 | Warner Bros. | true | false |
| 3 | - | Zathura: A Space Adventure | $422,132 | - | 213 | - | $1,981 | $1,408,388 | 1 | Sony Pictures Releasing | true | false |
| 4 | 1 | When a Stranger Calls | $303,345 | -45.6% | 180 | -6 | $1,685 | $2,073,251 | 3 | Sony Pictures Releasing | false | false |
| 5 | 6 | The Shaggy Dog | $283,091 | +3.7% | 121 | +37 | $2,339 | $1,683,908 | 2 | Buena Vista International | false | false |
| 6 | - | March of the Penguins | $261,240 | - | 40 | - | $6,531 | $262,906 | 1 | Roadshow Films | true | false |
| 7 | 3 | Walk the Line | $255,072 | -36.6% | 242 | -36 | $1,054 | $10,161,678 | 9 | 20th Century Fox International | false | false |
| 8 | 2 | The Pink Panther | $253,422 | -48.8% | 207 | -30 | $1,224 | $3,065,382 | 4 | 20th Century Fox International | false | false |
| 9 | - | Basic Instinct 2 | $252,865 | - | 184 | - | $1,374 | $252,865 | 1 | 20th Century Fox International | true | false |
| 10 | 9 | Match Point | $172,117 | -27.6% | 71 | -1 | $2,424 | $2,417,015 | 5 | Icon Film Distribution | false | false |
| 11 | 5 | Æon Flux | $155,551 | -59.9% | 162 | -12 | $960 | $1,596,792 | 3 | United International Pictures | false | false |
| 12 | - | The World's Fastest Indian | $148,770 | - | 178 | - | $835 | $150,912 | - | Becker Film Group | - | false |
| 13 | 8 | Cry Wolf | $104,028 | -58.2% | 144 | -2 | $722 | $438,025 | 2 | United International Pictures | false | false |
| 14 | 10 | A History of Violence | $97,522 | -54% | 76 | -5 | $1,283 | $1,572,352 | 4 | Roadshow Films | false | false |
| 15 | 15 | Capote | $94,633 | -28.3% | 50 | -1 | $1,892 | $1,572,352 | 6 | Sony Pictures Releasing | false | false |
| 16 | 16 | Brokeback Mountain | $78,624 | -39.3% | 87 | -10 | $903 | $6,244,753 | 10 | Roadshow Films | false | false |
| 17 | 11 | Tristan + Isolde | $62,171 | -64.8% | 103 | -44 | $603 | $718,654 | 3 | 20th Century Fox International | false | false |
| 18 | 17 | Syriana | $56,156 | -48.4% | 64 | -16 | $877 | $2,609,545 | 7 | Warner Bros. | false | false |
| 19 | 13 | Yours, Mine & Ours | $54,651 | -66.7% | 53 | +1 | $1,031 | $533,504 | 3 | Sony Pictures Releasing | false | false |
| 20 | - | Manual of Love | $47,403 | - | 9 | - | $5,267 | $197,008 | 2 | Palace Films | false | false |
