| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: The Meltdown | $1,354,843 | - | 189 | - | $7,168 | $1,537,782 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Inside Man | $344,280 | -17% | 65 | - | $5,296 | $937,742 | 2 | United International Pictures | false | false |
| 3 | - | V for Vendetta | $278,483 | - | 46 | - | $6,053 | $290,550 | 1 | Warner Bros. | true | false |
| 4 | - | Basic Instinct 2 | $143,010 | - | 64 | - | $2,234 | $143,010 | 1 | Independent Films | true | false |
| 5 | 2 | Date Movie | $104,680 | -36.9% | 49 | -1 | $2,136 | $609,349 | 3 | 20th Century Fox International | false | false |
| 6 | 3 | Brokeback Mountain | $79,198 | -25.4% | 40 | +1 | $1,979 | $1,565,949 | 7 | A-Film Distribution | false | false |
| 7 | 5 | The New World | $56,911 | -40.9% | 35 | - | $1,626 | $202,377 | 159 | RCV Film Distribution | false | false |
| 8 | 4 | Big Momma's House 2 | $53,656 | -48.9% | 63 | -12 | $851 | $2,358,289 | 7 | 20th Century Fox International | false | false |
| 9 | 8 | Bolletjes blues! | $41,641 | -31% | 14 | -1 | $2,974 | $118,080 | 2 | Benelux Film Distributors | false | false |
| 10 | 16 | Capote | $38,465 | +41.1% | 8 | +6 | $4,808 | $83,402 | 2 | Sony Pictures Releasing | false | false |
| 11 | 9 | A Thousand Kisses | $33,680 | -37.8% | 38 | -6 | $886 | $377,076 | 4 | A-Film Distribution | false | false |
| 12 | 10 | Nanny McPhee | $33,548 | -35% | 100 | -3 | $335 | $1,969,488 | 8 | United International Pictures | false | false |
| 13 | 7 | Syriana | $32,131 | -51.8% | 27 | -4 | $1,190 | $658,698 | 5 | Warner Bros. | false | false |
| 14 | - | Running Scared | $27,139 | - | 27 | - | $1,005 | $61,818 | 1 | Benelux Film Distributors | true | false |
| 15 | - | Romance & Cigarettes | $25,799 | - | 9 | - | $2,866 | $28,334 | 1 | A-Film Distribution | true | false |
| 16 | 18 | March of the Penguins | $22,382 | -9.7% | 33 | -1 | $678 | $1,056,952 | 15 | Paradiso Entertainment | false | false |
| 17 | 12 | Crash | $20,672 | -44.4% | 17 | -5 | $1,216 | $1,061,663 | 24 | Independent Films | false | false |
| 18 | 6 | The Pink Panther | $20,545 | -69.9% | 35 | -40 | $587 | $803,781 | 5 | 20th Century Fox International | false | false |
| 19 | 19 | The White Massai | $20,323 | -9.5% | 11 | - | $1,847 | $78,467 | 3 | Benelux Film Distributors | false | false |
| 20 | 17 | Tsotsi | $19,850 | -24.5% | 14 | -1 | $1,417 | $184,591 | 4 | Moonlight Films | false | false |
