| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: The Meltdown | $3,829,121 | - | 388 | - | $9,868 | $3,866,730 | 1 | 20th Century Fox International | true | false |
| 2 | - | She's the Man | $901,165 | - | 138 | - | $6,530 | $901,165 | 1 | Roadshow Films | true | false |
| 3 | 1 | Inside Man | $900,055 | -33.2% | 218 | -10 | $4,128 | $3,160,227 | 2 | United International Pictures | false | false |
| 4 | 2 | V for Vendetta | $685,003 | -42.3% | 202 | - | $3,391 | $3,282,377 | 2 | Warner Bros. | false | false |
| 5 | - | The World's Fastest Indian | $655,674 | - | 192 | - | $3,414 | $812,002 | 1 | Becker Film Group | true | false |
| 6 | 6 | March of the Penguins | $206,725 | -20.9% | 41 | +1 | $5,042 | $566,381 | 2 | Roadshow Films | false | false |
| 7 | 3 | Zathura: A Space Adventure | $145,231 | -65.6% | 180 | -33 | $806 | $1,661,676 | 2 | Sony Pictures Releasing | false | false |
| 8 | 7 | Walk the Line | $141,613 | -44.5% | 170 | -72 | $833 | $10,620,630 | 10 | 20th Century Fox International | false | false |
| 9 | 5 | The Shaggy Dog | $129,168 | -54.4% | 107 | -14 | $1,207 | $1,928,052 | 3 | Buena Vista International | false | false |
| 10 | 4 | When a Stranger Calls | $127,631 | -57.9% | 150 | -30 | $850 | $2,316,554 | 4 | Sony Pictures Releasing | false | false |
| 11 | 9 | Basic Instinct 2 | $120,116 | -52.5% | 175 | -9 | $686 | $481,161 | 2 | 20th Century Fox International | false | false |
| 12 | 10 | Match Point | $112,059 | -34.9% | 61 | -10 | $1,837 | $2,638,442 | 6 | Icon Film Distribution | false | false |
| 13 | 19 | Yours, Mine & Ours | $73,078 | +33.7% | 89 | +36 | $821 | $629,487 | 4 | Sony Pictures Releasing | false | false |
| 14 | 15 | Capote | $61,490 | -35% | 41 | -9 | $1,499 | $1,687,395 | 7 | Sony Pictures Releasing | false | false |
| 15 | 8 | The Pink Panther | $59,433 | -76.5% | 130 | -77 | $457 | $3,256,839 | 5 | 20th Century Fox International | false | false |
| 16 | 16 | Brokeback Mountain | $52,567 | -33.1% | 65 | -22 | $808 | $6,465,229 | 11 | Roadshow Films | false | false |
| 17 | 20 | Manual of Love | $38,964 | -17.8% | 10 | +1 | $3,896 | $253,236 | 3 | Palace Films | false | false |
| 18 | 14 | A History of Violence | $35,137 | -64% | 37 | -39 | $949 | $1,678,401 | 5 | Roadshow Films | false | false |
| 19 | 11 | Æon Flux | $33,513 | -78.5% | 60 | -102 | $558 | $1,716,201 | 4 | United International Pictures | false | false |
| 20 | - | Water Canadian Release | $27,268 | - | 14 | - | $1,947 | $26,268 | - | Dendy Films | - | false |
