| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: The Meltdown | $3,163,966 | -17.4% | 390 | +2 | $8,112 | $8,614,104 | 2 | 20th Century Fox International | false | false |
| 2 | - | Scary Movie 4 | $2,242,628 | - | 246 | - | $9,116 | $2,242,628 | 1 | Buena Vista International | true | false |
| 3 | - | Failure to Launch | $1,108,663 | - | 220 | - | $5,039 | $1,108,663 | 1 | United International Pictures | true | false |
| 4 | 3 | Inside Man | $715,740 | -20.5% | 206 | -12 | $3,474 | $4,249,924 | 3 | United International Pictures | false | false |
| 5 | 2 | She's the Man | $657,423 | -27% | 138 | - | $4,763 | $1,950,718 | 2 | Roadshow Films | false | false |
| 6 | 5 | The World's Fastest Indian | $654,770 | -0.1% | 192 | - | $3,410 | $1,783,289 | 2 | Becker Film Group | false | false |
| 7 | 4 | V for Vendetta | $575,729 | -16% | 175 | -27 | $3,289 | $3,155,503 | 3 | Warner Bros. | false | false |
| 8 | 6 | March of the Penguins | $487,062 | +135.6% | 123 | +82 | $3,959 | $1,153,789 | 3 | Roadshow Films | false | false |
| 9 | 9 | The Shaggy Dog | $418,174 | +223.7% | 246 | +139 | $1,699 | $2,574,218 | 4 | Buena Vista International | false | false |
| 10 | 13 | Yours, Mine & Ours | $169,424 | +131.8% | 158 | +69 | $1,072 | $887,703 | 5 | Sony Pictures Releasing | false | false |
| 11 | 7 | Zathura: A Space Adventure | $109,138 | -24.9% | 162 | -18 | $673 | $1,879,323 | 3 | Sony Pictures Releasing | false | false |
| 12 | - | Water Canadian Release | $98,574 | - | 16 | - | $6,160 | $171,999 | 1 | Dendy Films | true | false |
| 13 | 8 | Walk the Line | $85,906 | -39.3% | 95 | -75 | $904 | $10,915,069 | 11 | 20th Century Fox International | false | false |
| 14 | - | The Squid and the Whale | $80,370 | - | 14 | - | $5,740 | $99,953 | 1 | Sony Pictures Releasing | true | false |
| 15 | 12 | Match Point | $78,931 | -29.6% | 45 | -16 | $1,754 | $2,779,486 | 7 | Icon Film Distribution | false | false |
| 16 | - | Tsotsi | $71,901 | - | 22 | - | $3,268 | $92,399 | 1 | Rialto Distribution | true | false |
| 17 | - | How Much Do You Love Me? | $52,854 | - | 7 | - | $7,550 | $125,907 | 1 | Palace Films | true | false |
| 18 | 14 | Capote | $49,172 | -20% | 28 | -13 | $1,756 | $1,783,995 | 8 | Sony Pictures Releasing | false | false |
| 19 | - | Wild Safari - A South African Adventure | $37,915 | - | 2 | - | $18,957 | $1,843,814 | 44 | IMAX | false | false |
| 20 | 16 | Brokeback Mountain | $35,976 | -31.6% | 53 | -12 | $678 | $6,347,050 | 12 | Roadshow Films | false | false |
