| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: The Meltdown | $5,249,504 | - | 538 | - | $9,757 | $5,249,504 | 1 | 20th Century Fox International | true | false |
| 2 | - | Scary Movie 4 | $3,431,899 | - | 403 | - | $8,515 | $3,431,899 | 1 | Buena Vista International | true | false |
| 3 | 1 | Inside Man | $785,614 | -53.6% | 271 | -30 | $2,898 | $6,065,740 | 3 | United International Pictures | false | false |
| 4 | - | The Wedding Director | $578,209 | - | 209 | - | $2,766 | $578,209 | 1 | 01 Distribution | true | false |
| 5 | 3 | Just Like Heaven | $309,085 | -51.3% | 187 | -7 | $1,652 | $1,374,074 | 2 | United International Pictures | false | false |
| 6 | 2 | The Wild | $215,754 | -84.1% | 343 | -45 | $629 | $2,753,895 | 2 | Buena Vista International | false | false |
| 7 | 5 | Il mio miglior nemico | $205,482 | -62.4% | 110 | -75 | $1,868 | $22,363,679 | 7 | Filmauro | false | false |
| 8 | 4 | Keeping Mum | $186,946 | -68.4% | 216 | -17 | $865 | $1,196,263 | 2 | 01 Distribution | false | false |
| 9 | 8 | The Caiman | $186,078 | -47% | 73 | -103 | $2,549 | $7,758,665 | 5 | Sacher Distribuzione | false | false |
| 10 | 14 | Ti lascio perché ti amo troppo | $154,948 | -16.3% | 42 | -5 | $3,689 | $567,365 | 2 | Mikado Film | false | false |
| 11 | 6 | The Fog | $132,368 | -69.9% | 130 | -3 | $1,018 | $845,809 | 2 | Sony Pictures Releasing | false | false |
| 12 | 13 | Notte prima degli esami | $104,017 | -55.1% | 57 | -32 | $1,824 | $14,576,492 | 10 | 01 Distribution | false | false |
| 13 | 10 | ...e se domani | $97,238 | -64.9% | 94 | -3 | $1,034 | $557,553 | 2 | Medusa Distribuzione | false | false |
| 14 | - | Atomised | $95,442 | - | 44 | - | $2,169 | $95,442 | 1 | Lucky Red | true | false |
| 15 | 7 | Tristan + Isolde | $83,020 | -80.3% | 101 | -175 | $821 | $1,799,585 | 3 | 20th Century Fox International | false | false |
| 16 | 15 | Where the Truth Lies | $70,285 | -54.9% | 61 | -10 | $1,152 | $343,008 | 2 | Fandango | false | false |
| 17 | 18 | Into Great Silence | $62,485 | -33% | 44 | -3 | $1,420 | $501,076 | 4 | Metacinema | false | false |
| 18 | 9 | Failure to Launch | $52,497 | -82.1% | 58 | -101 | $905 | $2,190,060 | 4 | United International Pictures | false | false |
| 19 | 12 | Basic Instinct 2 | $31,986 | -87.9% | 32 | -107 | $999 | $3,178,196 | 4 | Warner Bros. | false | false |
| 20 | 11 | Nanny McPhee | $30,684 | -88.7% | 90 | -133 | $340 | $1,301,035 | 3 | Eagle Pictures | false | false |
