| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Da Vinci Code | $11,114,109 | - | 910 | - | $12,213 | $11,114,109 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Volver | $1,303,076 | - | 298 | - | $4,372 | $1,303,076 | 1 | Warner Bros. | true | false |
| 3 | 1 | Mission: Impossible III | $578,185 | -61.4% | 332 | -280 | $1,741 | $6,473,304 | 3 | United International Pictures | false | false |
| 4 | 2 | Ice Age: The Meltdown | $545,995 | -50% | 284 | -130 | $1,922 | $22,256,159 | 5 | 20th Century Fox International | false | false |
| 5 | 3 | Take the Lead | $220,863 | -63.4% | 145 | -140 | $1,523 | $5,434,560 | 4 | Eagle Pictures | false | false |
| 6 | 4 | The Devil's Rejects | $198,906 | -63.7% | 197 | -35 | $1,009 | $950,361 | 2 | Eagle Pictures | false | false |
| 7 | 5 | The Valet | $175,896 | -59% | 159 | -27 | $1,106 | $747,478 | 2 | Medusa Distribuzione | false | false |
| 8 | 6 | Romance & Cigarettes | $132,732 | -56.8% | 111 | -3 | $1,195 | $1,109,046 | 3 | Nexo | false | false |
| 9 | 9 | Libero (Along the Ridge) | $97,089 | -37.3% | 73 | -1 | $1,329 | $585,920 | 3 | 01 Distribution | false | false |
| 10 | 8 | Inside Man | $59,816 | -68.3% | 38 | -62 | $1,574 | $8,672,113 | 7 | United International Pictures | false | false |
| 11 | - | 4-4-2 - Il gioco più bello del mondo | $58,962 | - | 101 | - | $583 | $58,962 | 1 | Medusa Distribuzione | true | false |
| 12 | 11 | The Wedding Director | $45,787 | -57.8% | 46 | -33 | $995 | $2,289,733 | 5 | 01 Distribution | false | false |
| 13 | 10 | Big Momma's House 2 | $39,116 | -70.4% | 82 | -17 | $477 | $208,039 | 2 | 20th Century Fox International | false | false |
| 14 | 7 | Scary Movie 4 | $37,793 | -85.7% | 41 | -130 | $921 | $9,340,400 | 5 | Buena Vista International | false | false |
| 15 | 15 | In ascolto | $22,864 | -50% | 5 | -138 | $4,572 | $362,742 | 4 | Medusa Distribuzione | false | false |
| 16 | 18 | Bubble | $19,736 | -51.5% | 25 | -4 | $789 | $80,632 | 2 | Mediafilm | false | false |
| 17 | 20 | Into Great Silence | $15,368 | -57.7% | 20 | -15 | $768 | $865,367 | 8 | Metacinema | false | false |
| 18 | - | Notte prima degli esami | $14,486 | - | 12 | - | $1,207 | $15,199,593 | 14 | 01 Distribution | false | false |
| 19 | - | The Cave of the Yellow Dog | $13,917 | - | 14 | - | $994 | $162,267 | 4 | BIM Distribuzione | false | false |
| 20 | 16 | Atomised | $12,640 | -70.8% | 17 | -15 | $743 | $514,310 | 5 | Lucky Red | false | false |
