| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Da Vinci Code | $1,533,340 | - | 129 | - | $11,886 | $1,533,340 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Mission: Impossible III | $203,815 | -47% | 97 | -4 | $2,101 | $1,520,770 | 3 | United International Pictures | false | false |
| 3 | 2 | Ice Age: The Meltdown | $116,038 | +3.9% | 79 | -38 | $1,468 | $5,642,497 | 8 | 20th Century Fox International | false | false |
| 4 | 3 | Heartbreak Hotel | $57,970 | -25.2% | 59 | -36 | $982 | $4,394,929 | 9 | Svensk Filmindustri (SF) | false | false |
| 5 | 4 | Scary Movie 4 | $41,181 | -27.1% | 35 | - | $1,176 | $895,756 | 6 | Buena Vista International | false | false |
| 6 | 5 | Inside Man | $15,207 | -45.9% | 30 | -1 | $506 | $974,528 | 8 | United International Pictures | false | false |
| 7 | 7 | Walk the Line | $14,492 | -23.5% | 28 | -2 | $517 | $1,583,159 | 16 | 20th Century Fox International | false | false |
| 8 | 6 | V for Vendetta | $12,421 | -35.3% | 15 | -27 | $828 | $1,533,639 | 10 | Sandrew Metronome Distribution Sverige AB | false | false |
| 9 | 10 | Big Momma's House 2 | $12,290 | -10.7% | 14 | -1 | $877 | $360,235 | 7 | 20th Century Fox International | false | false |
| 10 | 9 | When a Stranger Calls | $10,610 | -25.8% | 18 | -5 | $589 | $321,080 | 7 | Sony Pictures Releasing | false | false |
| 11 | 14 | Lassie | $10,285 | +30.8% | 23 | - | $447 | $189,311 | 7 | Svensk Filmindustri (SF) | false | false |
| 12 | 8 | Brokeback Mountain | $9,310 | -37.3% | 20 | -14 | $465 | $2,181,113 | 16 | Sandrew Metronome Distribution Sverige AB | false | false |
| 13 | 11 | Stoned | $7,279 | -43.7% | 20 | - | $363 | $45,149 | 3 | NonStop Entertainment | false | false |
| 14 | 12 | Underworld: Evolution | $4,944 | -52.8% | 9 | -11 | $549 | $141,228 | 5 | Sony Pictures Releasing | false | false |
| 15 | 17 | Time to Leave | $4,296 | -27.6% | 3 | - | $1,432 | $24,917 | 3 | Triangelfilm | false | false |
| 16 | 15 | Syriana | $3,841 | -45% | 8 | -2 | $480 | $499,585 | 11 | Sandrew Metronome Distribution Sverige AB | false | false |
| 17 | 13 | Firewall | $3,805 | -54.4% | 9 | -11 | $422 | $160,607 | 5 | Sandrew Metronome Distribution Sverige AB | false | false |
| 18 | 16 | Get Rich or Die Tryin' | $3,737 | -46.5% | 5 | - | $747 | $57,397 | 4 | United International Pictures | false | false |
| 19 | 19 | Hustle & Flow | $3,637 | -33.7% | 5 | - | $727 | $12,103 | 2 | United International Pictures | false | false |
