| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Superman Returns | $379,461 | - | 82 | - | $4,627 | $379,461 | 1 | Warner Bros. | true | false |
| 2 | 1 | Click | $209,177 | -62.3% | 48 | - | $4,357 | $640,958 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | Take the Lead | $190,683 | - | 31 | - | $6,151 | $190,683 | 1 | Roadshow Films | true | false |
| 4 | 2 | Over the Hedge | $186,888 | -58% | 80 | +1 | $2,336 | $514,871 | 2 | United International Pictures | false | false |
| 5 | 4 | Cars | $107,862 | -66.2% | 82 | - | $1,315 | $1,292,312 | 4 | Buena Vista International | false | false |
| 6 | 3 | The Fast and the Furious: Tokyo Drift | $99,998 | -70.6% | 56 | +1 | $1,785 | $896,009 | 3 | United International Pictures | false | false |
| 7 | 5 | The Break-Up | $39,052 | -73.9% | 41 | -7 | $952 | $608,967 | 4 | United International Pictures | false | false |
| 8 | 6 | The Da Vinci Code | $34,290 | -69.2% | 42 | -12 | $816 | $3,117,541 | 7 | Sony Pictures Releasing | false | false |
| 9 | - | The Mistress of Spices | $27,659 | - | 14 | - | $1,975 | $27,659 | 1 | Rialto Distribution | true | false |
| 10 | 8 | On a Clear Day | $26,701 | -49.6% | 20 | -1 | $1,335 | $323,684 | 6 | Icon Film Distribution | false | false |
| 11 | 9 | Tsotsi | $21,430 | -43.3% | 16 | +2 | $1,339 | $172,073 | 5 | Rialto Distribution | false | false |
| 12 | 7 | X-Men: The Last Stand | $16,538 | -76.3% | 34 | -12 | $486 | $1,794,014 | 6 | 20th Century Fox International | false | false |
| 13 | - | Aquamarine | $12,199 | - | 40 | - | $304 | $12,199 | 1 | 20th Century Fox International | true | false |
| 14 | 14 | Kinky Boots | $10,122 | -45.9% | 18 | -3 | $562 | $408,031 | 13 | Buena Vista International | false | false |
| 15 | 12 | Tara Road | $10,007 | -57.5% | 12 | +1 | $833 | $104,724 | 5 | Rialto Distribution | false | false |
| 16 | 15 | Samoan Wedding | $6,242 | -66.4% | 23 | +2 | $271 | $2,455,182 | 14 | Sony Pictures Releasing | false | false |
| 17 | 17 | Mrs. Henderson Presents | $5,159 | -55.2% | 24 | -4 | $214 | $897,657 | 14 | Hopscotch Films | false | false |
| 18 | 18 | Oyster Farmer | $4,921 | -55.3% | 21 | -1 | $234 | $80,147 | 13 | Dendy Films | false | false |
| 19 | 16 | March of the Penguins | $4,639 | -66.8% | 20 | - | $231 | $642,364 | 14 | Roadshow Films | false | false |
| 20 | 19 | Candy | $3,531 | -67.9% | 7 | -15 | $504 | $67,082 | 5 | Dendy Films | false | false |
