| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Over the Hedge | $357,968 | - | 192 | - | $1,864 | $458,994 | 1 | United International Pictures | true | false |
| 2 | 1 | Cars | $240,931 | +26% | 165 | - | $1,460 | $1,089,478 | 3 | Buena Vista International | false | false |
| 3 | 2 | The Da Vinci Code | $215,550 | +21.5% | 131 | -4 | $1,645 | $8,519,627 | 8 | Sony Pictures Releasing | false | false |
| 4 | 3 | Zoop in India | $191,650 | +58.1% | 102 | - | $1,878 | $398,769 | 2 | Independent Films | false | false |
| 5 | - | Just My Luck | $126,197 | - | 44 | - | $2,868 | $133,764 | 1 | 20th Century Fox International | true | false |
| 6 | 4 | The Break-Up | $116,589 | -3% | 60 | +1 | $1,943 | $916,945 | 4 | United International Pictures | false | false |
| 7 | 5 | United 93 | $105,849 | +24.6% | 30 | - | $3,528 | $224,896 | 2 | United International Pictures | false | false |
| 8 | - | She's the Man | $77,196 | - | 35 | - | $2,205 | $108,984 | 1 | RCV Film Distribution | true | false |
| 9 | 6 | Poseidon | $77,160 | -5.7% | 83 | -14 | $929 | $1,742,306 | 6 | Warner Bros. | false | false |
| 10 | 7 | The Omen | $28,441 | -27.9% | 29 | -16 | $980 | $458,836 | 5 | 20th Century Fox International | false | false |
| 11 | 11 | Marie Antoinette | $24,037 | +36.4% | 22 | - | $1,092 | $219,618 | 5 | A-Film Distribution | false | false |
| 12 | 8 | X-Men: The Last Stand | $23,584 | -32.8% | 28 | -45 | $842 | $1,944,124 | 7 | 20th Century Fox International | false | false |
| 13 | - | Tapas | $17,743 | - | 11 | - | $1,613 | $22,271 | 1 | Cinemien | true | false |
| 14 | 10 | Slither | $10,666 | -64.8% | 22 | - | $484 | $87,386 | 2 | Benelux Film Distributors | false | false |
| 15 | 9 | 16 Blocks | $10,070 | -69.8% | 24 | -14 | $419 | $256,433 | 4 | Benelux Film Distributors | false | false |
| 16 | 14 | Heading South | $8,165 | +51.5% | 4 | - | $2,041 | $52,036 | 4 | A-Film Distribution | false | false |
| 17 | 17 | Comedy of Power | $6,119 | +35.1% | 5 | - | $1,223 | $30,308 | 3 | Paradiso Entertainment | false | false |
| 18 | 16 | Tara Road | $4,718 | -2.1% | 9 | - | $524 | $20,510 | 2 | RCV Film Distribution | false | false |
| 19 | 12 | Mission: Impossible III | $4,377 | -63.9% | 9 | -20 | $486 | $2,773,801 | 10 | United International Pictures | false | false |
| 20 | - | Capote | $3,305 | - | 6 | - | $550 | $358,436 | 16 | Sony Pictures Releasing | false | false |
