| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Superman Returns | $3,422,340 | - | 560 | - | $6,111 | $4,913,604 | 1 | Warner Bros. | true | false |
| 2 | 1 | Cars | $2,243,058 | -31.6% | 556 | - | $4,034 | $7,999,858 | 2 | Buena Vista International | false | false |
| 3 | 2 | Los mánagers | $484,561 | -21.6% | 214 | -1 | $2,264 | $1,465,103 | 2 | Filmax | false | false |
| 4 | 3 | The Lake House | $442,275 | -27.6% | 227 | - | $1,948 | $2,710,794 | 3 | Warner Bros. | false | false |
| 5 | 6 | The Tiger and the Snow | $412,612 | -10.8% | 160 | - | $2,578 | $1,171,449 | 2 | 20th Century Fox International | false | false |
| 6 | 5 | Lord of War | $390,384 | -21.5% | 198 | -2 | $1,971 | $2,294,484 | 3 | Sony Pictures Releasing | false | false |
| 7 | 4 | The Hills Have Eyes | $336,189 | -37.5% | 277 | -7 | $1,213 | $2,177,709 | 3 | 20th Century Fox International | false | false |
| 8 | - | She's the Man | $327,405 | - | 152 | - | $2,153 | $327,405 | 1 | - | true | false |
| 9 | 7 | Scary Movie 4 | $243,877 | -43.6% | 250 | -75 | $975 | $4,967,593 | 4 | Buena Vista International | false | false |
| 10 | 8 | The Da Vinci Code | $239,486 | -29.6% | 191 | -80 | $1,253 | $33,096,805 | 9 | Sony Pictures Releasing | false | false |
| 11 | 9 | Over the Hedge | $172,464 | -48.1% | 310 | -91 | $556 | $7,316,947 | 5 | United International Pictures | false | false |
| 12 | 10 | RV | $134,694 | -49.6% | 174 | -26 | $774 | $1,269,200 | 3 | Sony Pictures Releasing | false | false |
| 13 | 11 | The Education of Fairies | $127,598 | -35% | 135 | -68 | $945 | $1,702,218 | 4 | Alta Films | false | false |
| 14 | - | Your Life in 65 Minutes | $113,999 | - | 92 | - | $1,239 | $113,999 | 1 | Alta Films | true | false |
| 15 | - | Anthony Zimmer | $97,046 | - | 41 | - | $2,366 | $97,046 | 1 | - | true | false |
| 16 | - | H6: Diario de un asesino | $65,550 | - | 91 | - | $720 | $65,550 | 1 | - | true | false |
| 17 | 13 | Asterix and the Vikings | $56,556 | -48.6% | 179 | -21 | $315 | $772,456 | 3 | DeAPlaneta | false | false |
| 18 | 12 | Just My Luck | $53,329 | -63.9% | 99 | -107 | $538 | $2,557,420 | 5 | 20th Century Fox International | false | false |
| 19 | 16 | To Paint or Make Love | $46,448 | -31.2% | 32 | - | $1,451 | $154,967 | 2 | Golem Distribución | false | false |
| 20 | 14 | X-Men: The Last Stand | $42,633 | -52% | 79 | -47 | $539 | $12,132,233 | 8 | 20th Century Fox International | false | false |
