| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: Dead Man's Chest | $241,179 | -31.9% | 89 | -6 | $2,709 | $3,497,002 | 4 | Buena Vista International | false | false |
| 2 | - | You, Me and Dupree | $186,017 | - | 40 | - | $4,650 | $186,017 | 1 | United International Pictures | true | false |
| 3 | 2 | The Lake House | $72,900 | -33.1% | 34 | - | $2,144 | $223,631 | 2 | Roadshow Films | false | false |
| 4 | 4 | Take the Lead | $52,242 | -27.4% | 31 | -1 | $1,685 | $879,315 | 5 | Roadshow Films | false | false |
| 5 | 3 | Superman Returns | $48,680 | -34.8% | 71 | +6 | $685 | $1,276,547 | 5 | Warner Bros. | false | false |
| 6 | 6 | Over the Hedge | $41,948 | -28.5% | 70 | +4 | $599 | $1,918,965 | 6 | United International Pictures | false | false |
| 7 | 5 | RV | $32,420 | -50.8% | 48 | -1 | $675 | $306,418 | 3 | Sony Pictures Releasing | false | false |
| 8 | 8 | Click | $26,372 | -36.9% | 38 | -2 | $694 | $1,263,707 | 6 | Sony Pictures Releasing | false | false |
| 9 | 7 | Final Destination 3 | $24,674 | -50.3% | 37 | - | $666 | $228,694 | 3 | Warner Bros. | false | false |
| 10 | 10 | Confetti | $17,791 | -30.4% | 22 | +1 | $808 | $53,037 | 2 | 20th Century Fox International | false | false |
| 11 | 9 | Cars | $17,013 | -42.2% | 61 | -6 | $278 | $2,039,612 | 8 | Buena Vista International | false | false |
| 12 | - | Breakfast on Pluto | $14,177 | - | 10 | - | $1,417 | $14,177 | 1 | Dendy Films | true | false |
| 13 | 12 | As It Is in Heaven | $13,405 | +19.7% | 11 | +2 | $1,218 | $253,884 | 31 | Rialto Distribution | false | false |
| 14 | 11 | On a Clear Day | $12,324 | -12.9% | 17 | -5 | $724 | $428,948 | 10 | Icon Film Distribution | false | false |
| 15 | 15 | Tsotsi | $8,676 | +3.9% | 17 | - | $510 | $244,945 | 9 | Rialto Distribution | false | false |
| 16 | 13 | Curious George | $7,991 | -22.3% | 35 | -4 | $228 | $80,578 | 3 | United International Pictures | false | false |
| 17 | 14 | The Mistress of Spices | $6,376 | -35.1% | 15 | -2 | $425 | $114,391 | 5 | Rialto Distribution | false | false |
| 18 | 16 | The Da Vinci Code | $5,142 | -25.3% | 18 | -1 | $285 | $3,324,090 | 11 | Sony Pictures Releasing | false | false |
| 19 | 17 | Kinky Boots | $4,840 | -15.7% | 15 | +3 | $322 | $453,848 | 17 | Buena Vista International | false | false |
| 20 | 19 | March of the Penguins | $4,152 | -13.6% | 21 | +4 | $197 | $685,317 | 18 | Roadshow Films | false | false |
