| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: Dead Man's Chest | $223,239 | -61.9% | 106 | -3 | $2,106 | $3,920,651 | 4 | Buena Vista International | false | false |
| 2 | - | Volver | $145,258 | - | 30 | - | $4,841 | $145,258 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Bañeros III, todopoderosos | $132,942 | -66.1% | 96 | -3 | $1,384 | $2,873,355 | 5 | Argentina Sono Film S.A.C.I. | false | false |
| 4 | 5 | The Break-Up | $130,176 | -51.5% | 40 | - | $3,254 | $466,272 | 2 | United International Pictures | false | false |
| 5 | - | Monster House | $118,782 | - | 43 | - | $2,762 | $118,782 | 1 | Sony Pictures Releasing | true | false |
| 6 | - | 16 Blocks | $118,515 | - | 31 | - | $3,823 | $118,515 | 1 | Distribution Company | true | false |
| 7 | - | The Hands | $91,014 | - | 32 | - | $2,844 | $91,014 | 1 | Primer Plano Film Group | true | false |
| 8 | 3 | Over the Hedge | $75,816 | -75.7% | 104 | -39 | $729 | $2,545,657 | 5 | United International Pictures | false | false |
| 9 | 4 | El ratón Pérez | $63,131 | -78.3% | 101 | -9 | $625 | $2,302,366 | 6 | Buena Vista International | false | false |
| 10 | 7 | Superman Returns | $38,211 | -69.5% | 48 | -43 | $796 | $1,524,159 | 5 | Warner Bros. | false | false |
| 11 | 9 | Prime | $34,211 | -28.4% | 25 | -3 | $1,368 | $1,236,840 | 12 | Distribution Company | false | false |
| 12 | 6 | Cars | $30,491 | -79.7% | 67 | -36 | $455 | $3,062,251 | 7 | Buena Vista International | false | false |
| 13 | 10 | Premonition | $19,745 | -41.9% | 11 | - | $1,795 | $118,435 | 3 | Pachamama Cine | false | false |
| 14 | 8 | Garfield: A Tail of Two Kitties | $16,013 | -76.5% | 50 | -14 | $320 | $798,335 | 6 | 20th Century Fox International | false | false |
| 15 | 11 | Comedy of Power | $12,690 | -59.2% | 13 | -1 | $976 | $188,654 | 4 | Alfa Films | false | false |
| 16 | - | Curious George | $12,519 | - | 30 | - | $417 | $12,519 | 1 | United International Pictures | true | false |
| 17 | 12 | Patoruzito: The Great Adventure | $8,894 | -68.8% | 20 | -29 | $444 | $1,427,293 | 7 | Warner Bros. | false | false |
| 18 | 13 | Live and Become | $8,856 | -45.4% | 6 | - | $1,476 | $242,962 | 9 | Distribution Company | false | false |
| 19 | 15 | The Libertine | $8,527 | -22% | 18 | +4 | $473 | $134,704 | 8 | Distribution Company | false | false |
| 20 | 18 | Sunday Lunch 2006 Re-release | $6,694 | -20.3% | 7 | +1 | $956 | $113,052 | 7 | CDI Films | false | false |
