| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Cars | $3,284,477 | - | 637 | - | $5,156 | $5,321,679 | 1 | Buena Vista International | true | false |
| 2 | 4 | Lucky Number Slevin | $888,552 | +269.7% | 304 | +123 | $2,922 | $1,339,309 | 2 | Moviemax | false | false |
| 3 | 1 | Garfield: A Tail of Two Kitties | $599,451 | -45% | 312 | - | $1,921 | $2,685,852 | 2 | 20th Century Fox International | false | false |
| 4 | - | The Hills Have Eyes | $460,484 | - | 249 | - | $1,849 | $549,588 | 1 | 20th Century Fox International | true | false |
| 5 | - | Little Man | $202,243 | - | 101 | - | $2,002 | $202,243 | 1 | Sony Pictures Releasing | true | false |
| 6 | 3 | Domino | $200,402 | -52.5% | 239 | -15 | $838 | $1,069,347 | 2 | Eagle Pictures | false | false |
| 7 | - | C.R.A.Z.Y. | $61,196 | - | 80 | - | $764 | $76,011 | 1 | Istituto Luce | true | false |
| 8 | - | The Dark Sea | $56,661 | - | 30 | - | $1,888 | $56,661 | 1 | 01 Distribution | true | false |
| 9 | - | Time | $53,469 | - | 36 | - | $1,485 | $58,986 | 1 | Mikado Film | true | false |
| 10 | 5 | The Man | $40,127 | -71.6% | 81 | -66 | $495 | $703,960 | 3 | Eagle Pictures | false | false |
| 11 | - | Alien Autopsy | $33,892 | - | 56 | - | $605 | $33,892 | 1 | Warner Bros. | true | false |
| 12 | 6 | The Fast and the Furious: Tokyo Drift | $31,215 | -71.6% | 43 | -86 | $725 | $4,213,459 | 7 | United International Pictures | false | false |
| 13 | 7 | United 93 | $28,445 | -67.7% | 29 | -56 | $980 | $2,956,967 | 8 | United International Pictures | false | false |
| 14 | 14 | Volver | $26,601 | -14.7% | 19 | -20 | $1,400 | $8,538,220 | 15 | Warner Bros. | false | false |
| 15 | 10 | The Da Vinci Code | $26,111 | -54.5% | 20 | -25 | $1,305 | $36,621,606 | 15 | Sony Pictures Releasing | false | false |
| 16 | 9 | More Ants in the Pants 2006 Re-release | $13,607 | -78.7% | 23 | -32 | $591 | $520,745 | 4 | Mediafilm | false | false |
| 17 | 15 | Notte prima degli esami | $10,540 | -63.1% | 15 | -28 | $702 | $15,905,030 | 28 | 01 Distribution | false | false |
| 18 | 17 | A Prairie Home Companion | $9,878 | -43.2% | 7 | -9 | $1,411 | $1,686,150 | 13 | Medusa Distribuzione | false | false |
| 19 | - | Orchestra Seats | $9,021 | - | 8 | - | $1,127 | $431,631 | 11 | DNC Entertainment | false | false |
| 20 | 8 | See No Evil | $6,667 | -90.3% | 16 | -72 | $416 | $1,023,761 | 5 | Mediafilm | false | false |
