| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Lake House | $148,315 | - | 28 | - | $5,296 | $148,315 | 1 | Warner Bros. | true | false |
| 2 | - | United 93 | $82,949 | - | 20 | - | $4,147 | $82,949 | 1 | United International Pictures | true | false |
| 3 | 2 | Volver | $71,879 | -22.2% | 31 | +1 | $2,318 | $572,407 | 4 | 20th Century Fox International | false | false |
| 4 | 5 | Click | $71,360 | -1.9% | 31 | +1 | $2,301 | $320,793 | 3 | Sony Pictures Releasing | false | false |
| 5 | - | Fuerza aérea sociedad anónima | $68,684 | - | 17 | - | $4,040 | $68,684 | 1 | Distribution Company | true | false |
| 6 | 1 | The Sentinel | $68,015 | -27.6% | 40 | -1 | $1,700 | $388,709 | 3 | 20th Century Fox International | false | false |
| 7 | 3 | Lady in the Water | $63,487 | -27.9% | 25 | +1 | $2,539 | $171,346 | 2 | Warner Bros. | false | false |
| 8 | 6 | The Break-Up | $55,844 | -19.4% | 40 | - | $1,396 | $780,762 | 5 | United International Pictures | false | false |
| 9 | 7 | The Hands | $51,693 | -17.6% | 48 | +9 | $1,076 | $381,538 | 4 | Primer Plano Film Group | false | false |
| 10 | 8 | Monster House | $51,110 | -4.2% | 46 | -1 | $1,111 | $383,378 | 4 | Sony Pictures Releasing | false | false |
| 11 | 4 | Pirates of the Caribbean: Dead Man's Chest | $47,993 | -34.3% | 62 | -20 | $774 | $4,285,431 | 7 | Buena Vista International | false | false |
| 12 | 9 | 16 Blocks | $45,532 | -14.6% | 31 | - | $1,468 | $416,663 | 4 | Distribution Company | false | false |
| 13 | 10 | The Fast and the Furious: Tokyo Drift | $34,090 | -21.4% | 30 | - | $1,136 | $196,216 | 3 | United International Pictures | false | false |
| 14 | - | Cry Wolf | $27,372 | - | 16 | - | $1,710 | $27,372 | 1 | Distribution Company | true | false |
| 15 | 12 | The Ant Bully | $25,254 | -5.4% | 34 | - | $742 | $127,585 | 3 | Warner Bros. | false | false |
| 16 | - | Sofabed | $19,616 | - | 23 | - | $852 | $19,616 | 1 | Primer Plano Film Group | true | false |
| 17 | 11 | Open Water 2: Adrift | $18,112 | -46.1% | 31 | - | $584 | $59,720 | 2 | Alfa Films | false | false |
| 18 | 16 | Over the Hedge | $10,175 | -27.9% | 35 | -21 | $290 | $2,626,657 | 8 | United International Pictures | false | false |
| 19 | 14 | Prime | $9,909 | -48.8% | 9 | -9 | $1,101 | $1,310,973 | 15 | Distribution Company | false | false |
| 20 | 13 | Bañeros III, todopoderosos | $9,790 | -60.5% | 38 | -20 | $257 | $3,018,987 | 8 | Argentina Sono Film S.A.C.I. | false | false |
