| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Miami Vice | $76,273 | -41.3% | 50 | - | $1,525 | $244,923 | 2 | United International Pictures | false | false |
| 2 | - | Snakes on a Plane | $72,029 | - | 46 | - | $1,565 | $72,029 | 1 | Distribution Company | true | false |
| 3 | 2 | The Lake House | $64,505 | -35.4% | 27 | - | $2,389 | $372,463 | 3 | Warner Bros. | false | false |
| 4 | 5 | Volver | $44,186 | -21.5% | 30 | - | $1,472 | $710,696 | 6 | 20th Century Fox International | false | false |
| 5 | 3 | Fuerza aérea sociedad anónima | $38,908 | -40.8% | 19 | +1 | $2,047 | $226,236 | 3 | Distribution Company | false | false |
| 6 | 4 | Click | $38,103 | -37% | 31 | - | $1,229 | $401,897 | 5 | Sony Pictures Releasing | false | false |
| 7 | - | Transamerica | $34,777 | - | 11 | - | $3,161 | $34,777 | 1 | Alfa Films | true | false |
| 8 | 6 | The Jacket | $28,219 | -44.7% | 28 | - | $1,007 | $94,543 | 2 | Alfa Films | false | false |
| 9 | 11 | The Break-Up | $27,018 | -30.5% | 40 | - | $675 | $874,281 | 7 | United International Pictures | false | false |
| 10 | 9 | Lady in the Water | $26,791 | -36.1% | 24 | - | $1,116 | $268,127 | 4 | Warner Bros. | false | false |
| 11 | 7 | United 93 | $24,880 | -49.4% | 20 | - | $1,244 | $192,663 | 3 | United International Pictures | false | false |
| 12 | 10 | The Sentinel | $24,867 | -37% | 39 | -1 | $637 | $478,752 | 5 | 20th Century Fox International | false | false |
| 13 | 13 | The Hands | $21,881 | -40.7% | 46 | -1 | $475 | $471,731 | 6 | Primer Plano Film Group | false | false |
| 14 | 14 | Monster House | $19,973 | -38.3% | 48 | +1 | $416 | $465,989 | 6 | Sony Pictures Releasing | false | false |
| 15 | 8 | My Super Ex-Girlfriend | $19,572 | -55.3% | 23 | +3 | $850 | $76,445 | 2 | 20th Century Fox International | false | false |
| 16 | - | The Road to San Diego | $18,381 | - | 21 | - | $875 | $18,381 | 1 | 20th Century Fox International | true | false |
| 17 | 15 | 16 Blocks | $18,037 | -37.3% | 30 | -1 | $601 | $482,686 | 6 | Distribution Company | false | false |
| 18 | 16 | Pirates of the Caribbean: Dead Man's Chest | $13,414 | -50.6% | 28 | -18 | $479 | $4,345,055 | 9 | Buena Vista International | false | false |
| 19 | 17 | The Fast and the Furious: Tokyo Drift | $10,747 | -53% | 29 | -1 | $370 | $248,960 | 5 | United International Pictures | false | false |
| 20 | - | What the #$*! Do We (K)now!? 2005 Re-release | $10,597 | - | 8 | - | $1,324 | $10,597 | 1 | Pachamama Cine | true | false |
