| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | World Trade Center | $2,403,892 | - | 325 | - | $7,396 | $2,043,892 | 1 | United International Pictures | true | false |
| 2 | - | Click | $1,705,159 | - | 315 | - | $5,413 | $1,705,159 | 1 | Sony Pictures Releasing | true | false |
| 3 | 1 | Captain Alatriste: The Spanish Musketeer | $893,023 | -44% | 397 | -46 | $2,249 | $19,381,601 | 5 | 20th Century Fox International | false | false |
| 4 | 3 | Hoodwinked! | $736,223 | -35.4% | 258 | +2 | $2,853 | $2,115,020 | 2 | Manga Entertainment | false | false |
| 5 | 2 | Little Man | $731,281 | -48.9% | 250 | - | $2,925 | $4,852,412 | 3 | Sony Pictures Releasing | false | false |
| 6 | 4 | The Break-Up | $516,034 | -46.6% | 224 | -4 | $2,303 | $3,449,124 | 3 | United International Pictures | false | false |
| 7 | 5 | My Super Ex-Girlfriend | $466,619 | -49.9% | 299 | +1 | $1,560 | $1,604,931 | 2 | 20th Century Fox International | false | false |
| 8 | 6 | Salvador | $428,099 | -29.9% | 190 | +1 | $2,253 | $2,341,678 | 3 | Warner Bros. | false | false |
| 9 | 11 | The Wind that Shakes the Barley | $227,832 | -23.8% | 108 | -1 | $2,109 | $1,149,754 | 3 | Alta Films | false | false |
| 10 | 10 | Monster House | $226,736 | -41.7% | 231 | -55 | $981 | $4,693,220 | 5 | Sony Pictures Releasing | false | false |
| 11 | 8 | The Lazarus Child | $221,672 | -46.7% | 144 | -1 | $1,539 | $755,999 | 2 | - | false | false |
| 12 | 7 | Miami Vice | $217,553 | -56.1% | 219 | -64 | $993 | $4,136,568 | 4 | United International Pictures | false | false |
| 13 | - | Vete de mí | $150,297 | - | 72 | - | $2,087 | $150,297 | 1 | United International Pictures | true | false |
| 14 | 13 | The Ant Bully | $148,792 | -46.3% | 201 | -56 | $740 | $1,846,559 | 4 | Warner Bros. | false | false |
| 15 | 9 | La máquina de bailar | $146,003 | -64.4% | 245 | -4 | $595 | $653,124 | 2 | United International Pictures | false | false |
| 16 | 12 | Pirates of the Caribbean: Dead Man's Chest | $121,056 | -56.8% | 151 | -76 | $801 | $36,101,439 | 8 | Buena Vista International | false | false |
| 17 | 17 | Nine Lives | $111,232 | +6.1% | 23 | +5 | $4,836 | $267,642 | 2 | Versus Entertainment | false | false |
| 18 | 14 | Garfield: A Tail of Two Kitties | $109,978 | -52.2% | 190 | -67 | $578 | $8,253,813 | 6 | 20th Century Fox International | false | false |
| 19 | - | The Distance | $97,154 | - | 123 | - | $789 | $97,154 | 1 | Filmax | true | false |
| 20 | 15 | United 93 | $77,176 | -58.8% | 110 | -6 | $701 | $3,406,354 | 6 | United International Pictures | false | false |
