| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Illusionist | $149,011 | +23.5% | 29 | - | $5,138 | $310,451 | 2 | Alfa Films | false | false |
| 2 | 2 | World Trade Center | $67,603 | -25.3% | 40 | - | $1,690 | $180,383 | 2 | United International Pictures | false | false |
| 3 | 3 | The Devil Wears Prada | $55,753 | +8.1% | 35 | - | $1,592 | $699,071 | 6 | 20th Century Fox International | false | false |
| 4 | 4 | Open Season | $55,236 | +15.6% | 49 | -1 | $1,127 | $351,744 | 4 | Sony Pictures Releasing | false | false |
| 5 | - | The Covenant | $53,900 | - | 29 | - | $1,858 | $53,900 | 1 | Sony Pictures Releasing | true | false |
| 6 | 9 | Barnyard | $47,674 | +53.9% | 32 | - | $1,489 | $159,164 | 3 | United International Pictures | false | false |
| 7 | - | Heading South | $43,228 | - | 13 | - | $3,325 | $43,228 | 1 | Pachamama Cine | true | false |
| 8 | 5 | The Guardian | $42,367 | -6.2% | 47 | - | $901 | $341,886 | 4 | Buena Vista International | false | false |
| 9 | 7 | You, Me and Dupree | $41,225 | +14.1% | 30 | - | $1,374 | $361,123 | 5 | United International Pictures | false | false |
| 10 | 6 | Pulse | $33,233 | -20.7% | 25 | - | $1,329 | $177,243 | 3 | Distribution Company | false | false |
| 11 | 8 | The Lake House | $27,166 | -13.4% | 27 | - | $1,006 | $665,222 | 9 | Warner Bros. | false | false |
| 12 | - | Thank You for Smoking | $26,938 | - | 12 | - | $2,244 | $26,938 | 1 | 20th Century Fox International | true | false |
| 13 | - | Born and Bred | $25,124 | - | 13 | - | $1,932 | $25,124 | 1 | Distribution Company | true | false |
| 14 | 10 | Cheese Head | $22,810 | -19.5% | 20 | - | $1,140 | $116,664 | 3 | Primer Plano Film Group | false | false |
| 15 | 11 | Little Miss Sunshine | $20,559 | -12.7% | 13 | -1 | $1,581 | $102,052 | 3 | 20th Century Fox International | false | false |
| 16 | - | The Road to Guantanamo | $14,917 | - | 12 | - | $1,243 | $14,917 | 1 | Alfa Films | true | false |
| 17 | 13 | Click | $14,515 | -10.6% | 31 | - | $468 | $655,643 | 11 | Sony Pictures Releasing | false | false |
| 18 | 12 | Yo Presidente | $14,320 | -36.2% | 13 | - | $1,101 | $46,467 | 2 | Distribution Company | false | false |
| 19 | 15 | Volver | $13,988 | -3.5% | 26 | -1 | $538 | $916,509 | 12 | 20th Century Fox International | false | false |
| 20 | 17 | The Valet | $11,610 | -1.9% | 22 | +3 | $527 | $103,718 | 4 | Alfa Films | false | false |
