| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Casino Royale | $537,633 | -13.4% | 131 | - | $4,104 | $6,285,722 | 5 | Sony Pictures Releasing | false | false |
| 2 | 3 | The Holiday | $514,881 | +6.6% | 96 | +2 | $5,363 | $1,298,507 | 2 | United International Pictures | false | false |
| 3 | 2 | Happy Feet | $465,209 | -12.7% | 170 | - | $2,736 | $2,288,524 | 3 | Warner Bros. | false | false |
| 4 | 5 | Deja Vu | $283,177 | -12.1% | 71 | +1 | $3,988 | $740,806 | 2 | Buena Vista International | false | false |
| 5 | 4 | Eragon | $263,063 | -19.9% | 113 | - | $2,327 | $670,226 | 2 | 20th Century Fox International | false | false |
| 6 | 7 | Crusade in Jeans | $164,348 | +12.7% | 131 | - | $1,254 | $2,176,117 | 6 | Benelux Film Distributors | false | false |
| 7 | 6 | Perfume: The Story of a Murderer | $121,831 | -17.7% | 53 | +4 | $2,298 | $623,787 | 3 | RCV Film Distribution | false | false |
| 8 | 8 | Happy Family | $104,180 | -20.3% | 58 | +1 | $1,796 | $269,726 | 2 | RCV Film Distribution | false | false |
| 9 | - | Charlotte's Web | $79,520 | - | 117 | - | $679 | $91,005 | 1 | United International Pictures | true | false |
| 10 | 9 | Flushed Away | $69,324 | -21.9% | 151 | -12 | $459 | $672,898 | 4 | United International Pictures | false | false |
| 11 | 10 | The Departed | $47,676 | -23.8% | 38 | - | $1,254 | $2,077,846 | 7 | Warner Bros. | false | false |
| 12 | 11 | The Queen | $40,055 | -32.4% | 23 | - | $1,741 | $362,870 | 4 | A-Film Distribution | false | false |
| 13 | 12 | Plop in de stad | $39,602 | -17.8% | 101 | +1 | $392 | $105,967 | 2 | Independent Films | false | false |
| 14 | 13 | Babel | $36,694 | -21.1% | 20 | +1 | $1,834 | $1,191,837 | 8 | Independent Films | false | false |
| 15 | 14 | Black Book | $34,463 | -1.6% | 48 | -11 | $717 | $9,028,224 | 15 | A-Film Distribution | false | false |
| 16 | 16 | Borat | $25,144 | -5.4% | 14 | -7 | $1,796 | $3,041,929 | 8 | 20th Century Fox International | false | false |
| 17 | 15 | The Page Turner | $20,148 | -33.7% | 19 | +1 | $1,060 | $183,463 | 4 | Benelux Film Distributors | false | false |
| 18 | - | The Nativity Story | $14,760 | - | 32 | - | $461 | $29,148 | 3 | Benelux Film Distributors | false | false |
| 19 | - | Snow Cake | $11,513 | - | 8 | - | $1,439 | $13,664 | 1 | A-Film Distribution | true | false |
| 20 | 20 | A Christmoose Carol 2006 Re-release | $6,518 | -8.4% | 13 | - | $501 | $16,969 | 2 | Buena Vista International | false | false |
