| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | Happy Feet | $1,064,389 | +128.8% | 171 | +1 | $6,224 | $4,100,463 | 4 | Warner Bros. | false | false |
| 2 | 1 | Casino Royale | $680,400 | +26.6% | 127 | -4 | $5,357 | $7,640,152 | 6 | Sony Pictures Releasing | false | false |
| 3 | 2 | The Holiday | $658,538 | +27.9% | 96 | - | $6,859 | $2,410,892 | 3 | United International Pictures | false | false |
| 4 | 6 | Crusade in Jeans | $339,575 | +106.6% | 131 | - | $2,592 | $2,839,227 | 7 | Benelux Film Distributors | false | false |
| 5 | 4 | Deja Vu | $334,711 | +18.2% | 71 | - | $4,714 | $1,319,719 | 3 | Buena Vista International | false | false |
| 6 | 5 | Eragon | $331,834 | +26.1% | 113 | - | $2,936 | $1,349,577 | 3 | 20th Century Fox International | false | false |
| 7 | 9 | Charlotte's Web | $288,021 | +262.2% | 117 | - | $2,461 | $645,187 | 2 | United International Pictures | false | false |
| 8 | 10 | Flushed Away | $208,314 | +200.5% | 151 | - | $1,379 | $1,066,239 | 5 | United International Pictures | false | false |
| 9 | 13 | Plop in de stad | $177,916 | +349.3% | 101 | - | $1,761 | $404,843 | 3 | Independent Films | false | false |
| 10 | 7 | Perfume: The Story of a Murderer | $165,172 | +35.6% | 52 | -1 | $3,176 | $890,649 | 4 | RCV Film Distribution | false | false |
| 11 | 8 | Happy Family | $126,619 | +21.5% | 58 | - | $2,183 | $520,885 | 3 | RCV Film Distribution | false | false |
| 12 | 11 | The Departed | $72,950 | +53% | 28 | -10 | $2,605 | $2,217,241 | 8 | Warner Bros. | false | false |
| 13 | 15 | Black Book | $70,168 | +103.6% | 47 | -1 | $1,492 | $9,125,272 | 16 | A-Film Distribution | false | false |
| 14 | 12 | The Queen | $63,524 | +58.6% | 23 | - | $2,761 | $486,174 | 5 | A-Film Distribution | false | false |
| 15 | 14 | Babel | $55,916 | +52.4% | 20 | - | $2,795 | $1,279,222 | 9 | Independent Films | false | false |
| 16 | 16 | Borat | $30,526 | +21.4% | 14 | - | $2,180 | $3,109,677 | 9 | 20th Century Fox International | false | false |
| 17 | 17 | The Page Turner | $27,356 | +35.8% | 18 | -1 | $1,519 | $231,748 | 5 | Benelux Film Distributors | false | false |
| 18 | 19 | Snow Cake | $13,608 | +18.2% | 8 | - | $1,701 | $37,563 | 2 | A-Film Distribution | false | false |
| 19 | 18 | The Nativity Story | $8,387 | -43.2% | 14 | -18 | $599 | $77,678 | 4 | Benelux Film Distributors | false | false |
| 20 | - | Unaccompanied Minors | $4,577 | - | 14 | - | $326 | $26,580 | 3 | Warner Bros. | false | false |
