| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Happy Feet | $1,157,473 | +8.7% | 171 | - | $6,768 | $5,986,957 | 5 | Warner Bros. | false | false |
| 2 | 2 | Casino Royale | $755,808 | +11.1% | 128 | +1 | $5,904 | $8,825,782 | 7 | Sony Pictures Releasing | false | false |
| 3 | - | Saw III | $655,235 | - | 60 | - | $10,920 | $751,616 | 1 | Independent Films | true | false |
| 4 | 3 | The Holiday | $641,997 | -2.5% | 96 | - | $6,687 | $3,463,311 | 4 | United International Pictures | false | false |
| 5 | 4 | Crusade in Jeans | $404,507 | +19.1% | 131 | - | $3,087 | $3,455,309 | 8 | Benelux Film Distributors | false | false |
| 6 | 7 | Charlotte's Web | $373,650 | +29.7% | 110 | -7 | $3,396 | $1,242,023 | 3 | United International Pictures | false | false |
| 7 | 5 | Deja Vu | $345,263 | +3.2% | 71 | - | $4,862 | $1,860,528 | 4 | Buena Vista International | false | false |
| 8 | 6 | Eragon | $318,438 | -4% | 113 | - | $2,818 | $1,847,274 | 4 | 20th Century Fox International | false | false |
| 9 | 8 | Flushed Away | $261,170 | +25.4% | 110 | -41 | $2,374 | $1,487,554 | 6 | United International Pictures | false | false |
| 10 | 9 | Plop in de stad | $205,714 | +15.6% | 101 | - | $2,036 | $731,756 | 4 | Independent Films | false | false |
| 11 | 10 | Perfume: The Story of a Murderer | $182,066 | +10.2% | 52 | - | $3,501 | $1,160,304 | 5 | RCV Film Distribution | false | false |
| 12 | 11 | Happy Family | $169,500 | +33.9% | 58 | - | $2,922 | $818,565 | 4 | RCV Film Distribution | false | false |
| 13 | 13 | Black Book | $78,313 | +11.6% | 44 | -3 | $1,779 | $9,190,887 | 17 | A-Film Distribution | false | false |
| 14 | 12 | The Departed | $72,398 | -0.8% | 28 | - | $2,585 | $2,302,112 | 9 | Warner Bros. | false | false |
| 15 | - | The Illusionist | $69,366 | - | 15 | - | $4,624 | $102,115 | 1 | Independent Films | true | false |
| 16 | 15 | Babel | $67,472 | +20.7% | 21 | +1 | $3,212 | $1,359,892 | 10 | Independent Films | false | false |
| 17 | 14 | The Queen | $65,842 | +3.6% | 21 | -2 | $3,135 | $588,055 | 6 | A-Film Distribution | false | false |
| 18 | 17 | The Page Turner | $31,098 | +13.7% | 19 | +1 | $1,636 | $280,329 | 6 | Benelux Film Distributors | false | false |
| 19 | 16 | Borat | $20,092 | -34.2% | 12 | -2 | $1,674 | $3,114,832 | 10 | 20th Century Fox International | false | false |
| 20 | - | XTC Just Don't Do It | $17,071 | - | 14 | - | $1,219 | $2,840,321 | 14 | RCV Film Distribution | false | false |
