| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Blood Diamond | $590,869 | - | 80 | - | $7,385 | $615,716 | 1 | Warner Bros. | true | false |
| 2 | 1 | Casino Royale | $207,392 | -20.5% | 100 | -9 | $2,073 | $9,806,367 | 10 | Sony Pictures Releasing | false | false |
| 3 | 4 | The Holiday | $158,617 | -26.8% | 89 | -6 | $1,782 | $4,354,775 | 7 | United International Pictures | false | false |
| 4 | 5 | Happy Feet | $156,151 | -17.7% | 148 | -10 | $1,055 | $6,782,744 | 8 | Warner Bros. | false | false |
| 5 | 2 | Apocalypto | $145,425 | -40.2% | 81 | - | $1,795 | $906,943 | 3 | A-Film Distribution | false | false |
| 6 | 3 | Rocky Balboa | $121,868 | -48.2% | 60 | +2 | $2,031 | $407,841 | 2 | 20th Century Fox International | false | false |
| 7 | 7 | Deja Vu | $100,997 | -32.3% | 64 | -3 | $1,578 | $2,401,425 | 7 | Buena Vista International | false | false |
| 8 | 6 | Saw III | $90,027 | -42.2% | 61 | -1 | $1,475 | $1,503,811 | 4 | Independent Films | false | false |
| 9 | 9 | Perfume: The Story of a Murderer | $73,028 | -13.6% | 48 | -3 | $1,521 | $1,532,232 | 8 | RCV Film Distribution | false | false |
| 10 | 11 | Babel | $71,720 | +6.8% | 20 | -4 | $3,586 | $1,601,987 | 13 | Independent Films | false | false |
| 11 | 8 | Crusade in Jeans | $71,050 | -19.7% | 111 | -9 | $640 | $3,758,458 | 11 | Benelux Film Distributors | false | false |
| 12 | - | Little Children | $66,395 | - | 17 | - | $3,905 | $67,774 | 1 | A-Film Distribution | true | false |
| 13 | 10 | Happy Family | $60,467 | -13.6% | 56 | - | $1,079 | $1,059,709 | 7 | RCV Film Distribution | false | false |
| 14 | 12 | Charlotte's Web | $59,708 | -4.7% | 92 | -2 | $649 | $1,539,150 | 6 | United International Pictures | false | false |
| 15 | 14 | Black Book | $55,251 | -2.9% | 52 | +1 | $1,062 | $9,395,103 | 20 | A-Film Distribution | false | false |
| 16 | 15 | Flushed Away | $49,012 | -8.9% | 95 | -5 | $515 | $1,684,934 | 9 | United International Pictures | false | false |
| 17 | 16 | The Queen | $48,271 | -8.4% | 21 | - | $2,298 | $819,933 | 9 | A-Film Distribution | false | false |
| 18 | 17 | The Illusionist | $37,684 | -24.6% | 14 | -1 | $2,691 | $313,144 | 4 | Independent Films | false | false |
| 19 | 13 | Bobby | $37,658 | -34% | 18 | - | $2,092 | $134,474 | 2 | Benelux Film Distributors | false | false |
| 20 | 19 | Plop in de stad | $28,609 | -16.3% | 88 | -8 | $325 | $863,274 | 7 | Independent Films | false | false |
