| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Blood Diamond | $475,267 | -19.6% | 79 | -1 | $6,016 | $1,242,214 | 2 | Warner Bros. | false | false |
| 2 | - | The Pursuit of Happyness | $267,506 | - | 33 | - | $8,106 | $304,860 | 1 | Sony Pictures Releasing | true | false |
| 3 | - | Smokin' Aces | $200,627 | - | 39 | - | $5,144 | $247,121 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 2 | Casino Royale | $157,471 | -24.1% | 96 | -4 | $1,640 | $10,027,983 | 11 | Sony Pictures Releasing | false | false |
| 5 | 3 | The Holiday | $119,208 | -24.8% | 89 | - | $1,339 | $4,486,953 | 8 | United International Pictures | false | false |
| 6 | - | Arthur and the Invisibles | $102,769 | - | 86 | - | $1,194 | $127,612 | 1 | Independent Films | true | false |
| 7 | 4 | Happy Feet | $94,302 | -39.6% | 136 | -12 | $693 | $6,929,369 | 9 | Warner Bros. | false | false |
| 8 | 5 | Apocalypto | $88,470 | -39.2% | 79 | -2 | $1,119 | $1,032,080 | 4 | A-Film Distribution | false | false |
| 9 | 7 | Deja Vu | $73,091 | -27.6% | 61 | -3 | $1,198 | $2,503,412 | 8 | Buena Vista International | false | false |
| 10 | 10 | Babel | $72,276 | +0.8% | 34 | +14 | $2,125 | $1,705,938 | 14 | Independent Films | false | false |
| 11 | 12 | Little Children | $58,627 | -11.7% | 17 | - | $3,448 | $150,850 | 2 | A-Film Distribution | false | false |
| 12 | 9 | Perfume: The Story of a Murderer | $58,331 | -20.1% | 50 | +2 | $1,166 | $1,613,654 | 9 | RCV Film Distribution | false | false |
| 13 | 8 | Saw III | $50,395 | -44% | 50 | -11 | $1,007 | $1,579,557 | 5 | Independent Films | false | false |
| 14 | 6 | Rocky Balboa | $49,506 | -59.4% | 60 | - | $825 | $484,584 | 3 | 20th Century Fox International | false | false |
| 15 | 15 | Black Book | $49,456 | -10.5% | 49 | -3 | $1,009 | $9,499,002 | 21 | A-Film Distribution | false | false |
| 16 | 11 | Crusade in Jeans | $47,397 | -33.3% | 98 | -13 | $483 | $3,828,772 | 12 | Benelux Film Distributors | false | false |
| 17 | 17 | The Queen | $44,119 | -8.6% | 23 | +2 | $1,918 | $893,590 | 10 | A-Film Distribution | false | false |
| 18 | 13 | Happy Family | $41,191 | -31.9% | 56 | - | $735 | $1,115,505 | 8 | RCV Film Distribution | false | false |
| 19 | 14 | Charlotte's Web | $34,366 | -42.4% | 90 | -2 | $381 | $1,530,290 | 7 | United International Pictures | false | false |
| 20 | - | Ten Canoes | $32,993 | - | 13 | - | $2,537 | $37,436 | 1 | Cinemien | true | false |
