| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Night at the Museum | $754,205 | - | 85 | - | $8,873 | $891,994 | 1 | 20th Century Fox International | true | false |
| 2 | - | Taxi 4 | $733,050 | - | 56 | - | $13,090 | $736,795 | 1 | Belga Films | true | false |
| 3 | - | Firmin | $299,042 | - | 25 | - | $11,961 | $306,109 | 1 | N/A | true | false |
| 4 | - | La Vie En Rose | $292,328 | - | 25 | - | $11,693 | $292,328 | 1 | Cinéart | true | false |
| 5 | 1 | The Pursuit of Happyness | $223,102 | -28.5% | 28 | - | $7,967 | $597,024 | 2 | Sony Pictures Releasing | false | false |
| 6 | 2 | Blood Diamond | $215,986 | -28.4% | 51 | - | $4,235 | $1,586,015 | 4 | Warner Bros. | false | false |
| 7 | 3 | Charlotte's Web | $113,587 | -47.8% | 55 | +1 | $2,065 | $394,487 | 2 | Universal Pictures International (UPI) | false | false |
| 8 | 5 | The Departed | $94,536 | -31.2% | 58 | -12 | $1,629 | $3,101,694 | 8 | Warner Bros. | false | false |
| 9 | 6 | Odette Toulemonde | $93,578 | -29.4% | 17 | +1 | $5,504 | $269,530 | 2 | Alternative Films | false | false |
| 10 | 4 | Rocky Balboa | $86,803 | -58% | 50 | - | $1,736 | $905,949 | 3 | 20th Century Fox International | false | false |
| 11 | 10 | The Lives of Others | $65,918 | -20.2% | 17 | -1 | $3,877 | $280,945 | 3 | ABC Distribution | false | false |
| 12 | 11 | The Last King of Scotland | $65,737 | -11.2% | 15 | - | $4,382 | $159,163 | 2 | 20th Century Fox International | false | false |
| 13 | 9 | The Illusionist | $56,740 | -33.9% | 13 | -4 | $4,364 | $493,837 | 4 | Belga Films | false | false |
| 14 | - | It's a Boy Girl Thing | $48,596 | - | 12 | - | $4,049 | $48,596 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 15 | 7 | The Texas Chainsaw Massacre: The Beginning | $39,375 | -60.2% | 26 | -2 | $1,514 | $193,206 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 16 | 15 | Babel | $38,417 | -24.8% | 25 | -6 | $1,536 | $2,256,461 | 14 | Belga Films | false | false |
| 17 | - | An Inconvenient Truth | $37,904 | - | 16 | - | $2,369 | $1,482,031 | 19 | United International Pictures | false | false |
| 18 | 8 | John Tucker Must Die | $37,308 | -57% | 30 | - | $1,243 | $1,243,838 | 7 | 20th Century Fox International | false | false |
| 19 | 12 | Happy Feet | $32,893 | -54.1% | 75 | -7 | $438 | $4,491,531 | 11 | Warner Bros. | false | false |
| 20 | 19 | Ex Drummer | $28,392 | -24.3% | 11 | - | $2,581 | $124,786 | 3 | AF-Media | false | false |
