| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ghost Rider | $82,544 | - | 9 | - | $9,171 | $82,544 | 1 | Alexandra Films | true | false |
| 2 | 2 | Babel | $7,921 | -26.9% | 4 | - | $1,980 | $85,971 | 4 | Sunny Films | false | false |
| 3 | 1 | Volver | $6,793 | -62% | 5 | - | $1,358 | $26,354 | 2 | Big Bang Media | false | false |
| 4 | 4 | Blood Diamond | $6,214 | -28% | 9 | -5 | $690 | $159,910 | 5 | Alexandra Films | false | false |
| 5 | 6 | Breaking and Entering | $5,438 | -19.7% | 4 | - | $1,359 | $32,432 | 3 | Sunny Films | false | false |
| 6 | 3 | The Illusionist | $4,677 | -51% | 5 | - | $935 | $14,907 | 2 | Diema Films | false | false |
| 7 | - | Letters from Iwo Jima | $3,306 | - | 4 | - | $826 | $3,306 | 1 | Alexandra Films | true | false |
| 8 | 9 | The Queen | $3,306 | -21.8% | 4 | +1 | $826 | $8,960 | 2 | Prooptiki | false | false |
| 9 | 7 | The Pursuit of Happyness | $3,224 | -38.3% | 5 | - | $644 | $27,567 | 3 | Alexandra Films | false | false |
| 10 | - | Little Children | $2,989 | - | 3 | - | $996 | $2,989 | 1 | Alexandra Films | true | false |
| 11 | 10 | The Holiday | $2,717 | -25.9% | 6 | - | $452 | $72,238 | 6 | Prooptiki | false | false |
| 12 | 8 | Valley of Flowers | $2,596 | -41.4% | 5 | - | $519 | $19,656 | 3 | Alexandra Films | false | false |
| 13 | 15 | Monkeys in Winter | $867 | -34.4% | 5 | - | $173 | $8,444 | 3 | - | false | false |
| 14 | 13 | Night at the Museum | $838 | -47.9% | 5 | - | $167 | $137,146 | 8 | Alexandra Films | false | false |
| 15 | 5 | Notes on a Scandal | $816 | -89.2% | 5 | - | $163 | $12,166 | 2 | Alexandra Films | false | false |
| 16 | 16 | Happy Feet | $788 | -36.5% | 4 | - | $197 | $56,083 | 10 | Alexandra Films | false | false |
| 17 | 20 | Open Season | $718 | +7.2% | 3 | - | $239 | $122,434 | 16 | Alexandra Films | false | false |
| 18 | 12 | Prime | $674 | -60.3% | 3 | -2 | $224 | $32,400 | 5 | Diema Films | false | false |
| 19 | 32 | Wolfhound | $474 | +420.9% | 5 | +3 | $94 | $31,425 | 7 | Diema Films | false | false |
| 20 | 14 | DOA: Dead or Alive | $424 | -72.1% | 5 | -1 | $84 | $138,586 | 4 | Prooptiki | false | false |
| 21 | 17 | The Prestige | $407 | -58.5% | 6 | - | $67 | $70,505 | 7 | Alexandra Films | false | false |
| 22 | 18 | Stormbreaker | $283 | -70.5% | 5 | -1 | $56 | $10,834 | 4 | Diema Films | false | false |
| 23 | 11 | Captain Alatriste: The Spanish Musketeer | $249 | -89.5% | 8 | - | $31 | $58,274 | 6 | Alexandra Films | false | false |
| 24 | 25 | Garfield: A Tail of Two Kitties | $238 | +6.7% | 1 | - | $238 | $155,748 | 27 | Alexandra Films | false | false |
| 25 | 21 | The Departed | $209 | -66.7% | 2 | -1 | $104 | $161,414 | 18 | Alexandra Films | false | false |
| 26 | 24 | Sparrows in October | $172 | -42.1% | 4 | - | $43 | $668 | 2 | - | false | false |
| 27 | 23 | Eragon | $135 | -63.6% | 1 | -2 | $135 | $207,619 | 11 | Alexandra Films | false | false |
| 28 | 26 | Casino Royale | $74 | -61.5% | 1 | - | $74 | $228,535 | 14 | Alexandra Films | false | false |
| 29 | 29 | Cars | $72 | -36.3% | 1 | - | $72 | $88,807 | 30 | Sunny Films | false | false |
| 30 | 19 | Apocalypto | $66 | -90.6% | 3 | -2 | $22 | $215,036 | 10 | Alexandra Films | false | false |
| 31 | 36 | Over the Hedge | $64 | +30.6% | 2 | +1 | $32 | $11,534 | 26 | Prooptiki | false | false |
| 32 | 37 | The Devil Wears Prada | $44 | +12.8% | 2 | +1 | $22 | $155,583 | 20 | Alexandra Films | false | false |
| 33 | 31 | Children of Men | $35 | -63.5% | 1 | - | $35 | $32,753 | 16 | Prooptiki | false | false |
| 34 | 38 | Children of Wax | $33 | - | 1 | -1 | $33 | $2,697 | 5 | Prooptiki | false | false |
| 35 | 33 | Flushed Away | $32 | -61.4% | 1 | - | $32 | $8,593 | 12 | Prooptiki | false | false |
| 36 | 22 | Deja Vu | $10 | -97.6% | 1 | -5 | $10 | $266,570 | 13 | Sunny Films | false | false |
