| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Night at the Museum | $369,431 | -62.6% | 85 | - | $4,346 | $2,652,427 | 3 | 20th Century Fox International | false | false |
| 2 | 2 | Taxi 4 | $276,019 | -58.9% | 55 | -1 | $5,018 | $2,022,966 | 3 | Belga Films | false | false |
| 3 | 3 | Firmin | $229,784 | -49% | 25 | - | $9,191 | $1,153,885 | 3 | N/A | false | false |
| 4 | - | The Number 23 | $216,270 | - | 23 | - | $9,403 | $222,494 | 1 | Paradiso Entertainment | true | false |
| 5 | - | Dreamgirls | $193,495 | - | 35 | - | $5,528 | $306,287 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 4 | Ghost Rider | $190,475 | -49.2% | 30 | - | $6,349 | $594,803 | 2 | Sony Pictures Releasing | false | false |
| 7 | 6 | La Vie En Rose | $175,262 | -39.3% | 25 | - | $7,010 | $919,541 | 3 | Cinéart | false | false |
| 8 | 7 | Hannibal Rising | $155,856 | -45.5% | 40 | -1 | $3,896 | $521,206 | 2 | Benelux Film Distributors | false | false |
| 9 | 9 | Blood Diamond | $118,440 | -46.1% | 50 | -1 | $2,368 | $2,040,839 | 6 | Warner Bros. | false | false |
| 10 | 8 | Barnyard | $99,166 | -59.3% | 31 | - | $3,198 | $381,548 | 2 | Universal Pictures International (UPI) | false | false |
| 11 | 14 | The Departed | $91,031 | +14% | 51 | +8 | $1,784 | $3,359,896 | 10 | Warner Bros. | false | false |
| 12 | 5 | Charlotte's Web | $87,814 | -72.5% | 58 | - | $1,514 | $917,841 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | The Pursuit of Happyness | $86,539 | -59.1% | 28 | - | $3,090 | $988,986 | 4 | Sony Pictures Releasing | false | false |
| 14 | 15 | The Lives of Others | $72,381 | -3.3% | 13 | -2 | $5,567 | $492,487 | 5 | ABC Distribution | false | false |
| 15 | - | Little Children | $72,138 | - | 15 | - | $4,809 | $94,321 | 1 | Cinéart | true | false |
| 16 | 16 | The Last King of Scotland | $67,159 | -7.1% | 15 | - | $4,477 | $339,419 | 4 | 20th Century Fox International | false | false |
| 17 | 11 | Notes on a Scandal | $54,248 | -45.9% | 12 | - | $4,520 | $169,508 | 2 | 20th Century Fox International | false | false |
| 18 | - | Michou d'Auber | $46,571 | - | 18 | - | $2,587 | $47,227 | 1 | Victory Productions | true | false |
| 19 | 12 | Odette Toulemonde | $45,500 | -54.5% | 17 | - | $2,676 | $472,694 | 4 | Alternative Films | false | false |
| 20 | - | Scorpion | $35,155 | - | 8 | - | $4,394 | $35,155 | 1 | Cinéart | true | false |
