| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Night at the Museum | $482,129 | -29.2% | 101 | - | $4,773 | $2,308,548 | 3 | 20th Century Fox International | false | false |
| 2 | 2 | Ernst, Bobbie en de geslepen Onix | $300,702 | -31.7% | 107 | - | $2,810 | $1,467,007 | 3 | Independent Films | false | false |
| 3 | 3 | Dreamgirls | $228,620 | -26% | 40 | - | $5,715 | $712,187 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 5 | Blood Diamond | $196,490 | -18.2% | 79 | - | $2,487 | $2,686,928 | 6 | Warner Bros. | false | false |
| 5 | - | Kicks | $186,076 | - | 35 | - | $5,316 | $337,796 | 1 | Independent Films | true | false |
| 6 | 4 | Barnyard | $171,519 | -32.3% | 74 | - | $2,317 | $838,587 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | - | The Lives of Others | $162,643 | - | 22 | - | $7,392 | $180,178 | 1 | Cinemien | true | false |
| 8 | 6 | The Good Shepherd | $124,041 | -29.4% | 59 | - | $2,102 | $601,728 | 3 | Benelux Film Distributors | false | false |
| 9 | 7 | The Pursuit of Happyness | $120,348 | -22% | 33 | - | $3,646 | $1,248,609 | 5 | Sony Pictures Releasing | false | false |
| 10 | - | The Departed | $105,466 | - | 53 | - | $1,989 | $2,664,974 | 17 | Warner Bros. | false | false |
| 11 | 8 | Arthur and the Invisibles | $88,069 | -27.1% | 85 | - | $1,036 | $684,052 | 5 | Independent Films | false | false |
| 12 | 10 | Happy Feet | $83,930 | -19.1% | 89 | -6 | $943 | $7,515,003 | 13 | Warner Bros. | false | false |
| 13 | 9 | The Prestige | $80,872 | -26.8% | 30 | -1 | $2,695 | $691,882 | 4 | Warner Bros. | false | false |
| 14 | 11 | The Last King of Scotland | $71,912 | +5.9% | 15 | - | $4,794 | $356,963 | 4 | 20th Century Fox International | false | false |
| 15 | 16 | The Queen | $69,091 | +26.4% | 26 | -1 | $2,657 | $1,261,922 | 14 | A-Film Distribution | false | false |
| 16 | 15 | Notes on a Scandal | $55,241 | -4.3% | 12 | - | $4,603 | $153,830 | 2 | 20th Century Fox International | false | false |
| 17 | - | The Hitcher | $53,619 | - | 15 | - | $3,574 | $113,613 | 1 | RCV Film Distribution | true | false |
| 18 | 12 | Babel | $52,635 | -19.4% | 33 | -1 | $1,595 | $2,081,931 | 18 | Independent Films | false | false |
| 19 | 13 | Smokin' Aces | $41,223 | -36.1% | 40 | - | $1,030 | $737,440 | 5 | Universal Pictures International (UPI) | false | false |
| 20 | 14 | Casino Royale | $38,692 | -36.4% | 41 | -15 | $943 | $10,598,499 | 15 | Sony Pictures Releasing | false | false |
