| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Norbit | $130,489 | -35.4% | 46 | +1 | $2,836 | $385,019 | 2 | Paramount Pictures International | false | false |
| 2 | 2 | Music and Lyrics | $93,607 | -26% | 44 | - | $2,127 | $536,680 | 3 | Roadshow Films | false | false |
| 3 | - | The Marine | $82,151 | - | 37 | - | $2,220 | $82,151 | 1 | 20th Century Fox International | true | false |
| 4 | 3 | Notes on a Scandal | $77,268 | -2.2% | 12 | -8 | $6,439 | $195,293 | 2 | 20th Century Fox International | false | false |
| 5 | - | Smokin' Aces | $64,328 | - | 25 | - | $2,573 | $64,328 | 1 | Paramount Pictures International | true | false |
| 6 | 6 | Blood Diamond | $39,668 | -17.5% | 41 | +2 | $967 | $981,098 | 7 | Warner Bros. | false | false |
| 7 | 5 | The Pursuit of Happyness | $32,768 | -33.7% | 41 | -7 | $799 | $1,049,247 | 6 | Sony Pictures Releasing | false | false |
| 8 | 9 | The Queen | $32,297 | +29.1% | 49 | +34 | $659 | $1,534,842 | 11 | Icon Film Distribution | false | false |
| 9 | - | The Departed | $30,806 | - | 28 | - | $1,100 | $844,187 | 16 | Warner Bros. | false | false |
| 10 | 4 | Hannibal Rising | $27,282 | -48.7% | 27 | - | $1,010 | $101,792 | 2 | Roadshow Films | false | false |
| 11 | 10 | The Last King of Scotland | $26,003 | +16% | 20 | - | $1,300 | $178,942 | 4 | 20th Century Fox International | false | false |
| 12 | 8 | The History Boys | $23,507 | -14.5% | 11 | +1 | $2,137 | $279,457 | 6 | 20th Century Fox International | false | false |
| 13 | 7 | The Good Shepherd | $20,075 | -57.2% | 23 | -6 | $872 | $177,354 | 3 | Paramount Pictures International | false | false |
| 14 | 11 | Letters from Iwo Jima | $15,747 | -20.9% | 7 | - | $2,249 | $44,980 | 2 | Warner Bros. | false | false |
| 15 | 15 | Little Miss Sunshine | $14,860 | +22.3% | 27 | - | $550 | $778,347 | 21 | 20th Century Fox International | false | false |
| 16 | 12 | Babel | $12,815 | -23.7% | 16 | - | $800 | $470,404 | 9 | United International Pictures | false | false |
| 17 | 19 | Open Season | $9,261 | +1.7% | 44 | -2 | $210 | $955,262 | 8 | Sony Pictures Releasing | false | false |
| 18 | 14 | Casino Royale | $9,170 | -32.7% | 29 | +7 | $316 | $4,102,369 | 13 | Sony Pictures Releasing | false | false |
| 19 | 16 | Orchestra Seats | $9,051 | -19% | 11 | +2 | $822 | $36,398 | 3 | Rialto Distribution | false | false |
| 20 | 17 | Happy Feet | $8,475 | -23.5% | 52 | -16 | $162 | $2,940,226 | 10 | Roadshow Films | false | false |
