| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Wild Hogs | $202,614 | - | 41 | - | $4,941 | $202,614 | 1 | Buena Vista International | true | false |
| 2 | 1 | Norbit | $71,503 | -45.2% | 45 | -1 | $1,588 | $486,927 | 3 | Paramount Pictures International | false | false |
| 3 | 2 | Music and Lyrics | $64,102 | -31.5% | 44 | - | $1,456 | $639,122 | 4 | Roadshow Films | false | false |
| 4 | - | The Descent | $63,054 | - | 43 | - | $1,466 | $63,054 | 1 | Hoyts Distribution | true | false |
| 5 | 4 | Notes on a Scandal | $62,361 | -19.3% | 20 | +8 | $3,118 | $291,496 | 3 | 20th Century Fox International | false | false |
| 6 | 3 | The Marine | $45,568 | -44.5% | 36 | -1 | $1,265 | $159,943 | 2 | 20th Century Fox International | false | false |
| 7 | 5 | Smokin' Aces | $33,556 | -47.8% | 25 | - | $1,342 | $123,751 | 2 | Paramount Pictures International | false | false |
| 8 | - | Freedom Writers | $32,130 | - | 29 | - | $1,107 | $32,130 | 1 | Paramount Pictures International | true | false |
| 9 | 12 | The History Boys | $28,493 | +21.2% | 15 | +4 | $1,899 | $317,912 | 7 | 20th Century Fox International | false | false |
| 10 | - | The Science of Sleep | $24,850 | - | 18 | - | $1,380 | $57,277 | 1 | Rialto Distribution | true | false |
| 11 | 6 | Blood Diamond | $20,543 | -48.2% | 34 | -7 | $604 | $1,019,914 | 8 | Warner Bros. | false | false |
| 12 | 8 | The Queen | $20,443 | -36.7% | 40 | -9 | $511 | $1,575,557 | 12 | Icon Film Distribution | false | false |
| 13 | - | The Good German | $19,069 | - | 9 | - | $2,118 | $19,069 | 1 | Warner Bros. | true | false |
| 14 | 9 | The Departed | $18,566 | -39.7% | 26 | -2 | $714 | $876,118 | 17 | Warner Bros. | false | false |
| 15 | 11 | The Last King of Scotland | $13,356 | -48.6% | 18 | -2 | $742 | $201,864 | 5 | 20th Century Fox International | false | false |
| 16 | 7 | The Pursuit of Happyness | $13,223 | -59.6% | 26 | -15 | $508 | $1,076,799 | 7 | Sony Pictures Releasing | false | false |
| 17 | - | Dreamgirls | $9,964 | - | 27 | - | $369 | $481,381 | 8 | Paramount Pictures International | false | false |
| 18 | 15 | Little Miss Sunshine | $9,790 | -34.1% | 22 | -5 | $445 | $796,468 | 22 | 20th Century Fox International | false | false |
| 19 | 13 | The Good Shepherd | $9,486 | -52.7% | 16 | -7 | $592 | $195,086 | 4 | Paramount Pictures International | false | false |
| 20 | 14 | Letters from Iwo Jima | $8,851 | -43.8% | 6 | -1 | $1,475 | $61,323 | 3 | Warner Bros. | false | false |
