| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | 300 | $859,865 | - | 74 | - | $11,619 | $948,757 | 1 | Warner Bros. | true | false |
| 2 | 1 | Norbit | $465,269 | -30.5% | 84 | +30 | $5,538 | $1,320,907 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | Music and Lyrics | $290,523 | -22.3% | 96 | - | $3,026 | $1,547,751 | 3 | Warner Bros. | false | false |
| 4 | 3 | Hannibal Rising | $136,837 | -14.4% | 30 | -52 | $4,561 | $781,163 | 3 | Benelux Film Distributors | false | false |
| 5 | 4 | The Lives of Others | $136,837 | -10% | 30 | - | $4,561 | $781,163 | 4 | Cinemien | false | false |
| 6 | 6 | Blood Diamond | $73,985 | -20.2% | 60 | -4 | $1,233 | $3,053,389 | 9 | Warner Bros. | false | false |
| 7 | 5 | Night at the Museum | $73,463 | -44.9% | 100 | - | $734 | $2,866,614 | 6 | 20th Century Fox International | false | false |
| 8 | 8 | La Vie En Rose | $67,153 | -13.1% | 30 | +1 | $2,238 | $291,226 | 3 | RCV Film Distribution | false | false |
| 9 | 9 | Dreamgirls | $39,529 | -34% | 41 | - | $964 | $991,437 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | Ernst, Bobbie en de geslepen Onix | $36,720 | -53.3% | 104 | -4 | $353 | $1,715,071 | 6 | Independent Films | false | false |
| 11 | 12 | The Departed | $35,084 | -19.8% | 32 | -9 | $1,096 | $2,897,578 | 20 | Warner Bros. | false | false |
| 12 | 10 | Barnyard | $33,154 | -37.1% | 74 | +1 | $448 | $1,035,128 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | 18 | The Queen | $31,378 | +0.3% | 26 | - | $1,206 | $1,462,219 | 17 | A-Film Distribution | false | false |
| 14 | 13 | The Last King of Scotland | $29,340 | -24.6% | 15 | - | $1,956 | $522,826 | 7 | 20th Century Fox International | false | false |
| 15 | 17 | Notes on a Scandal | $25,951 | -18% | 12 | - | $2,162 | $291,935 | 5 | 20th Century Fox International | false | false |
| 16 | 20 | Babel | $24,041 | -5% | 22 | -3 | $1,092 | $2,220,347 | 21 | Independent Films | false | false |
| 17 | 15 | Freedom Writers | $23,010 | -33.1% | 18 | -2 | $1,278 | $143,743 | 3 | Universal Pictures International (UPI) | false | false |
| 18 | - | The Return | $22,952 | - | 7 | - | $3,278 | $24,641 | 1 | Universal Pictures International (UPI) | true | false |
| 19 | 11 | Dennis P. | $20,539 | -53.2% | 31 | - | $662 | $112,425 | 2 | RCV Film Distribution | false | false |
| 20 | 14 | The Good Shepherd | $18,959 | -45.4% | 19 | -14 | $997 | $778,913 | 6 | Benelux Film Distributors | false | false |
