| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Spider-Man 3 | $1,569,568 | - | 202 | - | $7,770 | $1,569,568 | 1 | Sony Pictures Releasing | true | false |
| 2 | 2 | The Lives of Others | $107,939 | -6.7% | 21 | - | $5,139 | $436,499 | 3 | Alfa Films | false | false |
| 3 | 1 | 300 | $89,968 | -32.2% | 79 | -7 | $1,138 | $3,667,497 | 6 | Warner Bros. | false | false |
| 4 | 3 | Perfect Stranger | $67,234 | -24% | 44 | -6 | $1,528 | $580,100 | 4 | Sony Pictures Releasing | false | false |
| 5 | 5 | The Messengers | $62,739 | -16.5% | 29 | - | $2,163 | $175,012 | 2 | Alfa Films | false | false |
| 6 | 4 | Meet the Robinsons | $58,608 | -30.4% | 81 | -20 | $723 | $1,719,160 | 6 | Buena Vista International | false | false |
| 7 | - | Fur: An Imaginary Portrait of Diane Arbus | $39,403 | - | 13 | - | $3,031 | $39,403 | 1 | Distribution Company | true | false |
| 8 | 6 | Disturbia | $38,478 | -23.1% | 27 | -3 | $1,425 | $234,496 | 3 | United International Pictures | false | false |
| 9 | - | 12:08 East of Bucharest | $34,014 | - | 11 | - | $3,092 | $34,014 | 1 | Zeta Films | true | false |
| 10 | 8 | The Number 23 | $33,646 | -19.7% | 26 | -1 | $1,294 | $687,587 | 7 | Distribution Company | false | false |
| 11 | 9 | Happily N'Ever After | $31,544 | -18.3% | 32 | -1 | $985 | $186,477 | 3 | Distribution Company | false | false |
| 12 | 7 | Wild Hogs | $23,586 | -46.7% | 29 | -12 | $813 | $279,871 | 4 | Buena Vista International | false | false |
| 13 | 11 | Music and Lyrics | $19,084 | -33.7% | 24 | -7 | $795 | $801,814 | 8 | Warner Bros. | false | false |
| 14 | 10 | Trust the Man | $17,034 | -44.6% | 16 | -5 | $1,064 | $131,265 | 3 | Pachamama Cine | false | false |
| 15 | - | Tres de corazones | $15,032 | - | 28 | - | $536 | $65,131 | 2 | Distribution Company | false | false |
| 16 | 14 | TMNT | $11,224 | -40.7% | 34 | -16 | $330 | $289,640 | 5 | Distribution Company | false | false |
| 17 | - | 7 Years | $11,142 | - | 5 | - | $2,228 | $36,419 | 2 | Impacto Cine | false | false |
| 18 | 12 | Shooter | $10,449 | -50.1% | 14 | -16 | $746 | $239,675 | 5 | United International Pictures | false | false |
| 19 | 13 | El amor y la ciudad | $10,041 | -47.2% | 6 | -5 | $1,673 | $69,951 | 3 | Primer Plano Film Group | false | false |
| 20 | - | The Reaping | $9,944 | - | 23 | - | $432 | $268,403 | 5 | Warner Bros. | false | false |
| 21 | - | A Wrecked Filmmaker | $9,728 | - | 9 | - | $1,080 | $9,278 | 1 | Primer Plano Film Group | true | false |
| 22 | 19 | Notes on a Scandal | $8,762 | +1.9% | 8 | -5 | $1,095 | $207,585 | 9 | 20th Century Fox International | false | false |
| 23 | 16 | Pathfinder | $7,669 | -46.1% | 11 | -4 | $697 | $176,061 | 7 | 20th Century Fox International | false | false |
| 24 | 18 | Scoop | $7,038 | -18.6% | 9 | -4 | $782 | $375,430 | 7 | CDI Films | false | false |
| 25 | 22 | The Queen | $5,031 | -21.7% | 13 | -7 | $387 | $836,392 | 11 | Distribution Company | false | false |
| 26 | 15 | Sunshine | $4,339 | -76.8% | 9 | -11 | $482 | $90,544 | 3 | 20th Century Fox International | false | false |
| 27 | 21 | Paris, I Love You | $4,100 | -36.3% | 4 | -6 | $1,025 | $282,381 | 8 | Impacto Cine | false | false |
| 28 | 20 | Epic Movie | $3,763 | -49.2% | 4 | -10 | $940 | $183,674 | 6 | 20th Century Fox International | false | false |
| 29 | 41 | Crank | $3,262 | +873.7% | 3 | +2 | $1,087 | $156,125 | 9 | Alfa Films | false | false |
| 30 | 17 | Kept and Dreamless | $2,580 | -70.4% | 8 | -5 | $322 | $15,627 | 2 | Primer Plano Film Group | false | false |
| 31 | - | The Wicker Man | $2,014 | - | 7 | - | $287 | $220,134 | 9 | Distribution Company | false | false |
| 32 | - | Argentina Beat | $2,010 | - | 4 | - | $502 | $2,010 | 1 | Primer Plano Film Group | true | false |
| 33 | 30 | Hoodwinked! | $1,730 | -44.3% | 8 | -4 | $216 | $818,945 | 13 | Alfa Films | false | false |
| 34 | - | The U.S. vs. John Lennon | $1,725 | - | 3 | - | $575 | $7,008 | 2 | Distribution Company | false | false |
| 35 | 23 | Arthur and the Invisibles | $1,203 | -79.4% | 9 | -26 | $133 | $117,531 | 5 | Alfa Films | false | false |
| 36 | - | Mothers | $891 | - | 2 | - | $445 | $891 | 1 | Primer Plano Film Group | true | false |
| 37 | 26 | Apocalypto | $810 | -80.4% | 5 | -14 | $162 | $842,168 | 14 | 20th Century Fox International | false | false |
| 38 | 24 | The Education of Fairies | $725 | -87% | 4 | -10 | $181 | $83,739 | 6 | Buena Vista International | false | false |
| 39 | 37 | Norbit | $698 | -18.8% | 2 | -2 | $349 | $244,838 | 9 | United International Pictures | false | false |
| 40 | 34 | Letters from Iwo Jima | $629 | -59.8% | 4 | -7 | $157 | $306,946 | 12 | Warner Bros. | false | false |
| 41 | 31 | Captain Alatriste: The Spanish Musketeer | $599 | -78.8% | 6 | -3 | $99 | $36,428 | 5 | 20th Century Fox International | false | false |
| 42 | 35 | Night at the Museum | $554 | -59% | 3 | -1 | $184 | $3,225,350 | 16 | 20th Century Fox International | false | false |
| 43 | 28 | Ghost Rider | $515 | -85.2% | 8 | -12 | $64 | $561,135 | 8 | Sony Pictures Releasing | false | false |
| 44 | 29 | Stranger Than Fiction | $498 | -85.5% | 4 | -8 | $124 | $178,089 | 9 | Sony Pictures Releasing | false | false |
| 45 | 25 | Who Says It's Easy? | $425 | -91.3% | 9 | -7 | $47 | $1,290,983 | 13 | Primer Plano Film Group | false | false |
| 46 | 33 | Blood Diamond | $317 | -86.2% | 3 | -5 | $105 | $889,676 | 13 | Warner Bros. | false | false |
| 47 | 38 | Funny Ha Ha 2007 Re-release | $204 | -63.7% | 1 | - | $204 | $2,208 | 3 | 791 Cine | false | false |
| 48 | 47 | C.R.A.Z.Y. | $194 | +7.8% | 1 | -6 | $194 | $48,262 | 8 | Alfa Films | false | false |
| 49 | 36 | Rocky Balboa | $98 | -92% | 4 | -4 | $24 | $409,538 | 10 | 20th Century Fox International | false | false |
| 50 | 42 | Time to Leave | $83 | -74.9% | 2 | -1 | $41 | $62,078 | 10 | Alfa Films | false | false |
| 51 | 27 | The Aerial | $80 | -97.9% | 1 | -4 | $80 | $16,838 | 3 | Pachamama Cine | false | false |
| 52 | 40 | Babel | $55 | -84.5% | 1 | -2 | $55 | $1,738,552 | 16 | United International Pictures | false | false |
| 53 | 48 | The Last King of Scotland | $54 | -61.2% | 1 | -10 | $54 | $160,068 | 12 | 20th Century Fox International | false | false |
| 54 | 39 | City in Heat | $17 | -96.2% | 1 | -2 | $17 | $32,165 | 7 | Alfa Films | false | false |
| 55 | 44 | Flushed Away | $6 | -98.1% | 1 | -2 | $6 | $1,587,691 | 18 | United International Pictures | false | false |
