| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Spider-Man 3 | $882,730 | -43.8% | 202 | - | $4,369 | $2,816,416 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | La Vie En Rose | $104,942 | - | 18 | - | $5,830 | $104,942 | 1 | Alfa Films | true | false |
| 3 | 2 | The Lives of Others | $87,097 | -19.3% | 22 | +1 | $3,958 | $549,554 | 4 | Alfa Films | false | false |
| 4 | - | Mr. Bean's Holiday | $71,097 | - | 15 | - | $4,739 | $71,097 | 1 | United International Pictures | true | false |
| 5 | 4 | Perfect Stranger | $53,054 | -21.1% | 41 | -3 | $1,294 | $644,236 | 5 | Sony Pictures Releasing | false | false |
| 6 | 3 | 300 | $50,242 | -44.2% | 86 | +7 | $584 | $3,717,739 | 7 | Warner Bros. | false | false |
| 7 | - | The Other | $48,547 | - | 14 | - | $3,467 | $48,547 | 1 | Distribution Company | true | false |
| 8 | 5 | The Messengers | $48,189 | -23.2% | 29 | - | $1,661 | $235,627 | 3 | Alfa Films | false | false |
| 9 | 8 | Disturbia | $31,853 | -17.2% | 27 | - | $1,179 | $272,697 | 4 | United International Pictures | false | false |
| 10 | 6 | Meet the Robinsons | $29,393 | -49.8% | 67 | -14 | $438 | $1,757,052 | 7 | Buena Vista International | false | false |
| 11 | 10 | The Number 23 | $24,664 | -26.7% | 26 | - | $948 | $719,980 | 8 | Distribution Company | false | false |
| 12 | 11 | Happily N'Ever After | $23,494 | -25.5% | 33 | +1 | $711 | $214,206 | 4 | Distribution Company | false | false |
| 13 | 7 | Fur: An Imaginary Portrait of Diane Arbus | $20,006 | -49.2% | 13 | - | $1,538 | $67,343 | 2 | Distribution Company | false | false |
| 14 | 9 | 12:08 East of Bucharest | $17,473 | -48.6% | 11 | - | $1,588 | $57,486 | 2 | Zeta Films | false | false |
| 15 | 12 | Wild Hogs | $14,428 | -38.8% | 31 | +2 | $465 | $298,534 | 5 | Buena Vista International | false | false |
| 16 | 14 | Trust the Man | $12,605 | -26% | 15 | -1 | $840 | $147,590 | 4 | Pachamama Cine | false | false |
| 17 | 13 | Music and Lyrics | $12,211 | -36% | 17 | -7 | $718 | $817,918 | 9 | Warner Bros. | false | false |
| 18 | 28 | Epic Movie | $9,403 | +149.9% | 10 | +6 | $940 | $193,410 | 7 | 20th Century Fox International | false | false |
| 19 | 16 | TMNT | $7,501 | -33.2% | 35 | +1 | $214 | $299,006 | 6 | Distribution Company | false | false |
| 20 | 26 | Sunshine | $7,442 | +71.5% | 15 | +6 | $496 | $98,862 | 4 | 20th Century Fox International | false | false |
| 21 | 15 | Tres de corazones | $7,003 | -53.4% | 27 | -1 | $259 | $75,741 | 3 | Distribution Company | false | false |
| 22 | 23 | Pathfinder | $6,849 | -10.7% | 9 | -2 | $761 | $184,903 | 8 | 20th Century Fox International | false | false |
| 23 | 22 | Notes on a Scandal | $6,498 | -25.8% | 4 | -4 | $1,624 | $216,205 | 10 | 20th Century Fox International | false | false |
| 24 | 18 | Shooter | $5,777 | -44.7% | 12 | -2 | $481 | $247,939 | 6 | United International Pictures | false | false |
| 25 | 20 | The Reaping | $5,215 | -47.6% | 14 | -9 | $372 | $275,943 | 6 | Warner Bros. | false | false |
| 26 | 17 | 7 Years | $4,852 | -56.5% | 5 | - | $970 | $43,456 | 3 | Impacto Cine | false | false |
| 27 | 41 | Captain Alatriste: The Spanish Musketeer | $4,568 | +662.6% | 6 | - | $761 | $41,121 | 6 | 20th Century Fox International | false | false |
| 28 | 21 | A Wrecked Filmmaker | $3,358 | -65.5% | 9 | - | $373 | $14,700 | 2 | Primer Plano Film Group | false | false |
| 29 | 27 | Paris, I Love You | $2,745 | -33% | 4 | - | $686 | $286,239 | 9 | Impacto Cine | false | false |
| 30 | 25 | The Queen | $2,428 | -51.7% | 10 | -3 | $242 | $840,242 | 12 | Distribution Company | false | false |
| 31 | 31 | The Wicker Man | $2,362 | +17.3% | 4 | -3 | $590 | $222,812 | 10 | Distribution Company | false | false |
| 32 | 29 | Crank | $1,749 | -46.4% | 3 | - | $583 | $158,498 | 10 | Alfa Films | false | false |
| 33 | 24 | Scoop | $1,468 | -79.1% | 4 | -5 | $367 | $378,303 | 8 | CDI Films | false | false |
| 34 | 38 | The Education of Fairies | $1,449 | +99.9% | 4 | - | $362 | $85,347 | 7 | Buena Vista International | false | false |
| 35 | 33 | Hoodwinked! | $1,371 | -20.8% | 11 | +3 | $124 | $820,496 | 14 | Alfa Films | false | false |
| 36 | 34 | The U.S. vs. John Lennon | $1,108 | -35.8% | 2 | -1 | $554 | $9,255 | 3 | Distribution Company | false | false |
| 37 | 35 | Arthur and the Invisibles | $915 | -23.9% | 8 | -1 | $114 | $118,584 | 6 | Alfa Films | false | false |
| 38 | 30 | Kept and Dreamless | $889 | -65.5% | 6 | -2 | $148 | $17,133 | 3 | Primer Plano Film Group | false | false |
| 39 | 32 | Argentina Beat | $827 | -58.9% | 4 | - | $206 | $3,696 | 2 | Primer Plano Film Group | false | false |
| 40 | 37 | Apocalypto | $618 | -23.7% | 6 | +1 | $103 | $843,161 | 15 | 20th Century Fox International | false | false |
| 41 | 54 | City in Heat | $596 | +3,405.9% | 2 | +1 | $298 | $32,777 | 8 | Alfa Films | false | false |
| 42 | 46 | Blood Diamond | $561 | +77% | 5 | +2 | $112 | $890,313 | 14 | Warner Bros. | false | false |
| 43 | 36 | Mothers | $508 | -43% | 2 | - | $254 | $1,610 | 2 | Primer Plano Film Group | false | false |
| 44 | 42 | Night at the Museum | $418 | -24.5% | 4 | +1 | $104 | $3,225,769 | 17 | 20th Century Fox International | false | false |
| 45 | 44 | Stranger Than Fiction | $231 | -53.6% | 3 | -1 | $77 | $178,364 | 10 | Sony Pictures Releasing | false | false |
| 46 | 53 | The Last King of Scotland | $223 | +313% | 1 | - | $223 | $160,421 | 13 | 20th Century Fox International | false | false |
| 47 | 40 | Letters from Iwo Jima | $222 | -64.7% | 5 | +1 | $44 | $307,431 | 13 | Warner Bros. | false | false |
| 48 | 47 | Funny Ha Ha 2007 Re-release | $196 | -3.9% | 1 | - | $196 | $2,689 | 4 | 791 Cine | false | false |
| 49 | - | Flags of Our Fathers | $116 | - | 1 | - | $116 | $208,156 | 16 | Warner Bros. | false | false |
| 50 | 49 | Rocky Balboa | $78 | -20.4% | 1 | -3 | $78 | $409,664 | 11 | 20th Century Fox International | false | false |
| 51 | 51 | The Aerial | $72 | -10% | 2 | +1 | $36 | $17,009 | 4 | Pachamama Cine | false | false |
| 52 | 48 | C.R.A.Z.Y. | $59 | -69.6% | 1 | - | $59 | $48,365 | 9 | Alfa Films | false | false |
| 53 | 52 | Babel | $55 | - | 1 | - | $55 | $1,738,658 | 17 | United International Pictures | false | false |
| 54 | 55 | Flushed Away | $13 | +116.7% | 1 | - | $13 | $1,587,713 | 19 | United International Pictures | false | false |
