| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Spider-Man 3 | $485,705 | -27.3% | 109 | +1 | $4,456 | $1,491,712 | 2 | N/A | false | false |
| 2 | - | Epic Movie | $108,275 | - | 31 | - | $3,492 | $108,275 | 1 | N/A | true | false |
| 3 | 3 | Wild Hogs | $64,157 | -40.8% | 32 | +2 | $2,004 | $760,869 | 4 | N/A | false | false |
| 4 | 2 | The Reaping | $62,878 | -44% | 45 | -2 | $1,397 | $911,576 | 4 | N/A | false | false |
| 5 | 4 | 13 segundos | $58,046 | -41.5% | 30 | - | $1,934 | $651,619 | 4 | N/A | false | false |
| 6 | - | Perfume: The Story of a Murderer | $42,796 | - | 19 | - | $2,252 | $82,689 | 1 | N/A | true | false |
| 7 | 5 | Pathfinder | $24,930 | -57.4% | 22 | -8 | $1,133 | $294,695 | 3 | N/A | false | false |
| 8 | 7 | A Virgin Grandmother | $22,788 | -20.6% | 16 | +1 | $1,424 | $853,132 | 11 | N/A | false | false |
| 9 | - | Cake | $15,118 | - | 10 | - | $1,511 | $16,748 | 1 | N/A | true | false |
| 10 | 8 | Keeping Mum | $14,573 | -45.5% | 12 | - | $1,214 | $55,244 | 2 | N/A | false | false |
| 11 | 10 | Primeval | $12,336 | -39.6% | 15 | -1 | $822 | $117,544 | 3 | N/A | false | false |
| 12 | 13 | Curse of the Golden Flower | $9,106 | -40.7% | 11 | - | $827 | $73,541 | 3 | N/A | false | false |
| 13 | 9 | Shooter | $8,020 | -62.3% | 22 | -7 | $364 | $488,603 | 5 | N/A | false | false |
| 14 | 6 | Meet the Robinsons | $7,512 | -78.5% | 41 | -13 | $183 | $1,706,232 | 7 | N/A | false | false |
| 15 | 15 | Lucky Number Slevin | $4,604 | -52.3% | 8 | +2 | $575 | $509,187 | 11 | N/A | false | false |
| 16 | 16 | Five Times Two | $4,389 | -46.9% | 2 | - | $2,194 | $31,544 | 3 | N/A | false | false |
| 17 | 11 | TMNT | $3,679 | -81.5% | 26 | -3 | $141 | $1,015,337 | 7 | N/A | false | false |
| 18 | 17 | Norbit | $1,949 | -75.4% | 6 | -9 | $324 | $1,373,612 | 10 | N/A | false | false |
| 19 | 14 | Step Up | $1,725 | -83.5% | 5 | -8 | $345 | $120,949 | 4 | N/A | false | false |
| 20 | 12 | Apocalypto | $1,280 | -92.6% | 8 | -13 | $160 | $430,712 | 5 | N/A | false | false |
| 21 | 18 | Ghost Rider | $21 | -99.5% | 1 | -10 | $21 | $1,199,026 | 7 | N/A | false | false |
