| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Spider-Man 3 | $489,214 | -44.6% | 202 | - | $2,421 | $3,478,149 | 3 | Sony Pictures Releasing | false | false |
| 2 | - | Fracture | $150,620 | - | 32 | - | $4,706 | $150,620 | 1 | Distribution Company | true | false |
| 3 | 2 | La Vie En Rose | $79,457 | -24.3% | 22 | +4 | $3,611 | $216,357 | 2 | Alfa Films | false | false |
| 4 | - | Zodiac | $64,958 | - | 20 | - | $3,247 | $64,958 | 1 | Warner Bros. | true | false |
| 5 | 3 | The Lives of Others | $59,882 | -31.2% | 24 | +2 | $2,495 | $633,923 | 5 | Alfa Films | false | false |
| 6 | 4 | Mr. Bean's Holiday | $41,095 | -42.2% | 15 | - | $2,739 | $125,899 | 2 | United International Pictures | false | false |
| 7 | 8 | The Messengers | $37,080 | -23.1% | 29 | - | $1,278 | $285,267 | 4 | Alfa Films | false | false |
| 8 | 5 | Perfect Stranger | $28,074 | -47.1% | 48 | +7 | $584 | $686,828 | 6 | Sony Pictures Releasing | false | false |
| 9 | 9 | Disturbia | $26,264 | -17.5% | 30 | +3 | $875 | $306,719 | 5 | United International Pictures | false | false |
| 10 | - | The Mistress of Spices | $24,975 | - | 9 | - | $2,775 | $24,975 | 1 | Pachamama Cine | true | false |
| 11 | 7 | The Other | $22,629 | -53.4% | 14 | - | $1,616 | $82,024 | 2 | Distribution Company | false | false |
| 12 | 6 | 300 | $21,547 | -57.1% | 52 | -34 | $414 | $3,739,286 | 8 | Warner Bros. | false | false |
| 13 | 11 | The Number 23 | $21,350 | -13.4% | 27 | +1 | $790 | $748,164 | 9 | Distribution Company | false | false |
| 14 | 12 | Happily N'Ever After | $18,186 | -22.6% | 32 | -1 | $568 | $236,932 | 5 | Distribution Company | false | false |
| 15 | 16 | Trust the Man | $16,653 | +32.1% | 21 | +6 | $793 | $167,127 | 5 | Pachamama Cine | false | false |
| 16 | 10 | Meet the Robinsons | $16,588 | -43.6% | 57 | -10 | $291 | $1,778,900 | 8 | Buena Vista International | false | false |
| 17 | 20 | Sunshine | $11,389 | +53% | 17 | +2 | $669 | $112,524 | 5 | 20th Century Fox International | false | false |
| 18 | 14 | 12:08 East of Bucharest | $9,315 | -46.7% | 11 | - | $846 | $71,231 | 3 | Zeta Films | false | false |
| 19 | 15 | Wild Hogs | $6,732 | -53.3% | 17 | -14 | $396 | $308,407 | 6 | Buena Vista International | false | false |
| 20 | 18 | Epic Movie | $6,344 | -32.5% | 13 | +3 | $488 | $202,177 | 8 | 20th Century Fox International | false | false |
| 21 | 17 | Music and Lyrics | $6,311 | -48.3% | 19 | +2 | $332 | $827,269 | 10 | Warner Bros. | false | false |
| 22 | - | Cocalero | $5,971 | - | 5 | - | $1,194 | $5,971 | 1 | Primer Plano Film Group | true | false |
| 23 | 22 | Pathfinder | $5,765 | -15.8% | 13 | +4 | $443 | $192,535 | 9 | 20th Century Fox International | false | false |
| 24 | 25 | The Reaping | $5,739 | +10% | 18 | +4 | $318 | $282,934 | 7 | Warner Bros. | false | false |
| 25 | - | The Best of Youth 2007 Re-release | $5,213 | - | 2 | - | $2,606 | $5,213 | 1 | IFA | true | false |
| 26 | 19 | TMNT | $5,062 | -32.5% | 34 | -1 | $148 | $305,779 | 7 | Distribution Company | false | false |
| 27 | 13 | Fur: An Imaginary Portrait of Diane Arbus | $4,618 | -76.9% | 13 | - | $355 | $76,324 | 3 | Distribution Company | false | false |
| 28 | 33 | Scoop | $3,551 | +141.9% | 8 | +4 | $443 | $382,317 | 9 | CDI Films | false | false |
| 29 | 24 | Shooter | $3,340 | -42.2% | 8 | -4 | $417 | $252,886 | 7 | United International Pictures | false | false |
| 30 | 23 | Notes on a Scandal | $3,331 | -48.7% | 4 | - | $832 | $221,217 | 11 | 20th Century Fox International | false | false |
| 31 | 21 | Tres de corazones | $2,224 | -68.2% | 17 | -10 | $130 | $79,972 | 4 | Distribution Company | false | false |
| 32 | 26 | 7 Years | $2,092 | -56.9% | 5 | - | $418 | $46,877 | 4 | Impacto Cine | false | false |
| 33 | 29 | Paris, I Love You | $2,001 | -27.1% | 3 | -1 | $667 | $289,086 | 10 | Impacto Cine | false | false |
| 34 | - | Changing Times | $1,623 | - | 2 | - | $811 | $65,034 | 9 | Alfa Films | false | false |
| 35 | 31 | The Wicker Man | $1,467 | -37.9% | 3 | -1 | $489 | $224,745 | 11 | Distribution Company | false | false |
| 36 | 30 | The Queen | $1,286 | -47% | 3 | -7 | $428 | $842,285 | 13 | Distribution Company | false | false |
| 37 | 27 | Captain Alatriste: The Spanish Musketeer | $1,179 | -74.2% | 2 | -4 | $589 | $43,359 | 7 | 20th Century Fox International | false | false |
| 38 | 32 | Crank | $1,153 | -34.1% | 3 | - | $384 | $160,126 | 11 | Alfa Films | false | false |
| 39 | 35 | Hoodwinked! | $829 | -39.5% | 5 | -6 | $165 | $821,825 | 15 | Alfa Films | false | false |
| 40 | 38 | Kept and Dreamless | $763 | -14.2% | 2 | -4 | $381 | $18,341 | 4 | Primer Plano Film Group | false | false |
| 41 | 28 | A Wrecked Filmmaker | $693 | -79.4% | 3 | -6 | $231 | $16,105 | 3 | Primer Plano Film Group | false | false |
| 42 | 37 | Arthur and the Invisibles | $492 | -46.2% | 12 | +4 | $41 | $119,388 | 7 | Alfa Films | false | false |
| 43 | 44 | Night at the Museum | $284 | -32.1% | 2 | -2 | $142 | $3,226,053 | 18 | 20th Century Fox International | false | false |
| 44 | - | Who Says It's Easy? | $278 | - | 1 | - | $278 | $1,291,820 | 15 | Primer Plano Film Group | false | false |
| 45 | 46 | The Last King of Scotland | $186 | -16.6% | 1 | - | $186 | $160,738 | 14 | 20th Century Fox International | false | false |
| 46 | 34 | The Education of Fairies | $162 | -88.8% | 3 | -1 | $54 | $85,823 | 8 | Buena Vista International | false | false |
| 47 | 50 | Rocky Balboa | $139 | +78.2% | 2 | +1 | $69 | $409,844 | 12 | 20th Century Fox International | false | false |
| 48 | 52 | C.R.A.Z.Y. | $129 | +118.6% | 2 | +1 | $64 | $48,509 | 10 | Alfa Films | false | false |
| 49 | 40 | Apocalypto | $113 | -81.7% | 3 | -3 | $37 | $843,537 | 16 | 20th Century Fox International | false | false |
| 50 | 42 | Blood Diamond | $66 | -88.2% | 3 | -2 | $22 | $890,567 | 15 | Warner Bros. | false | false |
| 51 | 45 | Stranger Than Fiction | $62 | -73.2% | 3 | - | $20 | $181,346 | 11 | Sony Pictures Releasing | false | false |
| 52 | 54 | Flushed Away | $19 | +46.2% | 1 | - | $19 | $1,587,733 | 20 | United International Pictures | false | false |
