| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Pirates of the Caribbean: At World's End | $952,349 | - | 38 | - | $25,061 | $952,349 | 1 | Buena Vista International | true | false |
| 2 | - | Spider-Man 3 | $131,787 | - | 83 | - | $1,587 | $2,674,919 | 4 | Sony Pictures Releasing | false | false |
| 3 | - | Papelucho y el marciano | $94,336 | - | 32 | - | $2,948 | $426,368 | 2 | Bazuca Films | false | false |
| 4 | - | Scoop | $19,987 | - | 6 | - | $3,331 | $109,268 | 3 | CDI Films | false | false |
| 5 | - | The Queen | $9,468 | - | 6 | - | $1,578 | $218,352 | 5 | Bazuca Films | false | false |
| 6 | - | The Reaping | $9,243 | - | 10 | - | $924 | $443,639 | 8 | Warner Bros. | false | false |
| 7 | - | The Good Shepherd | $7,507 | - | 6 | - | $1,251 | $91,661 | 5 | United International Pictures | false | false |
| 8 | - | Hoodwinked! | $4,906 | - | 13 | - | $377 | $240,741 | 5 | Transeuropa | false | false |
| 9 | - | Hard Candy | $4,525 | - | 3 | - | $1,508 | $19,524 | 2 | Bazuca Films | false | false |
| 10 | - | Pulse | $2,643 | - | 7 | - | $377 | $163,038 | 6 | Bazuca Films | false | false |
| 11 | - | Mr. Bean's Holiday | $2,616 | - | 9 | - | $290 | $306,453 | 8 | United International Pictures | false | false |
| 12 | - | Sunshine | $1,889 | - | 5 | - | $377 | $99,648 | 5 | 20th Century Fox International | false | false |
| 13 | - | Epic Movie | $1,744 | - | 7 | - | $249 | $162,411 | 6 | 20th Century Fox International | false | false |
| 14 | - | Meet the Robinsons | $1,650 | - | 6 | - | $275 | $515,621 | 8 | Buena Vista International | false | false |
| 15 | - | Apocalypto | $1,019 | - | 2 | - | $509 | $357,644 | 12 | 20th Century Fox International | false | false |
| 16 | - | Man About Town | $935 | - | 3 | - | $311 | $18,749 | 3 | Andes Films | false | false |
| 17 | - | Pathfinder | $880 | - | 4 | - | $220 | $121,807 | 7 | 20th Century Fox International | false | false |
| 18 | - | Happily N'Ever After | $851 | - | 4 | - | $212 | $141,859 | 6 | Bazuca Films | false | false |
| 19 | - | 300 | $735 | - | 4 | - | $183 | $1,500,771 | 9 | Warner Bros. | false | false |
| 20 | - | TMNT | $663 | - | 5 | - | $132 | $232,499 | 8 | Bazuca Films | false | false |
| 21 | - | Music and Lyrics | $398 | - | 2 | - | $199 | $209,023 | 11 | Warner Bros. | false | false |
| 22 | - | Ghost Rider | $129 | - | 1 | - | $129 | $268,229 | 8 | Sony Pictures Releasing | false | false |
