| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: At World's End | $612,375 | -36.7% | 234 | -22 | $2,616 | $4,051,228 | 3 | Buena Vista International | false | false |
| 2 | 3 | Fracture | $113,493 | -1.3% | 32 | -1 | $3,546 | $651,465 | 4 | Distribution Company | false | false |
| 3 | 2 | Spider-Man 3 | $109,462 | -31.8% | 96 | -59 | $1,140 | $4,278,623 | 6 | Sony Pictures Releasing | false | false |
| 4 | - | Hostel: Part II | $93,076 | - | 28 | - | $3,324 | $93,076 | 1 | Sony Pictures Releasing | true | false |
| 5 | - | The Singer (Quand j'étais chanteur) | $73,406 | - | 14 | - | $5,243 | $73,406 | 1 | Distribution Company | true | false |
| 6 | - | 28 Weeks Later | $72,525 | - | 28 | - | $2,590 | $72,525 | 1 | 20th Century Fox International | true | false |
| 7 | 4 | Mr. Brooks | $47,529 | -32.8% | 24 | -1 | $1,980 | $135,498 | 2 | CDI Films | false | false |
| 8 | 5 | The Lives of Others | $43,965 | -14.3% | 24 | - | $1,831 | $837,111 | 8 | Alfa Films | false | false |
| 9 | 6 | Zodiac | $36,720 | -0.6% | 20 | - | $1,836 | $244,314 | 4 | Warner Bros. | false | false |
| 10 | 9 | La Vie En Rose | $30,625 | -7.5% | 23 | +2 | $1,331 | $393,116 | 5 | Alfa Films | false | false |
| 11 | - | The Science of Sleep | $25,532 | - | 11 | - | $2,321 | $25,532 | 1 | Pachamama Cine | true | false |
| 12 | 10 | Mr. Bean's Holiday | $24,456 | +6.3% | 15 | - | $1,630 | $212,893 | 5 | United International Pictures | false | false |
| 13 | - | A Stray Girlfriend | $23,466 | - | 12 | - | $1,955 | $23,466 | 1 | Primer Plano Film Group | true | false |
| 14 | 8 | The Host | $19,440 | -44.3% | 15 | -10 | $1,296 | $65,495 | 2 | Alfa Films | false | false |
| 15 | 7 | Fearless | $12,899 | -63.9% | 26 | - | $496 | $60,010 | 2 | Distribution Company | false | false |
| 16 | 11 | Disturbia | $12,893 | -31.2% | 14 | -3 | $920 | $367,524 | 8 | United International Pictures | false | false |
| 17 | 15 | Happily N'Ever After | $9,666 | +10% | 34 | +8 | $284 | $280,710 | 8 | Distribution Company | false | false |
| 18 | 13 | Perfect Stranger | $7,933 | -29.2% | 24 | -2 | $330 | $733,081 | 9 | Sony Pictures Releasing | false | false |
| 19 | 27 | The Reaping | $4,893 | +169.6% | 10 | +4 | $489 | $297,997 | 10 | Warner Bros. | false | false |
| 20 | 17 | Trust the Man | $4,741 | -15.5% | 11 | +5 | $431 | $202,296 | 8 | Pachamama Cine | false | false |
| 21 | 14 | The Messengers | $4,634 | -58.5% | 11 | -8 | $421 | $339,272 | 7 | Alfa Films | false | false |
| 22 | 22 | Meet the Robinsons | $3,992 | +12.7% | 14 | -3 | $285 | $1,808,839 | 11 | Buena Vista International | false | false |
| 23 | 21 | The Best of Youth 2007 Re-release | $3,991 | +0.8% | 2 | - | $1,995 | $23,730 | 4 | IFA | false | false |
| 24 | - | Argentina latente | $3,798 | - | 3 | - | $1,266 | $15,259 | 3 | Primer Plano Film Group | false | false |
| 25 | 12 | Time | $3,521 | -69.4% | 6 | -5 | $586 | $54,754 | 3 | Distribution Company | false | false |
| 26 | 19 | Fur: An Imaginary Portrait of Diane Arbus | $3,154 | -39.4% | 8 | - | $394 | $97,382 | 6 | Distribution Company | false | false |
| 27 | 20 | The Number 23 | $2,994 | -35.6% | 11 | - | $272 | $781,985 | 12 | Distribution Company | false | false |
| 28 | 16 | The Mistress of Spices | $2,922 | -49.4% | 5 | -4 | $584 | $63,017 | 4 | Pachamama Cine | false | false |
| 29 | 18 | The Other | $2,916 | -45.3% | 6 | -7 | $486 | $115,453 | 5 | Distribution Company | false | false |
| 30 | 32 | Crank | $1,796 | +77.3% | 4 | +1 | $449 | $165,314 | 14 | Alfa Films | false | false |
| 31 | 31 | Sunshine | $1,783 | +70.1% | 11 | +8 | $162 | $120,707 | 8 | 20th Century Fox International | false | false |
| 32 | 24 | 12:08 East of Bucharest | $1,632 | -36.2% | 2 | -2 | $816 | $83,283 | 6 | Zeta Films | false | false |
| 33 | 29 | 300 | $1,585 | +16.1% | 4 | -4 | $396 | $3,766,396 | 11 | Warner Bros. | false | false |
| 34 | 23 | Maria Bethânia - Pedrinha de Aruanda | $1,327 | -56.5% | 2 | +1 | $663 | $11,019 | 3 | 791 Cine | false | false |
| 35 | 28 | Cocalero | $1,270 | -22% | 4 | - | $317 | $19,120 | 4 | Primer Plano Film Group | false | false |
| 36 | 33 | The Wicker Man | $1,131 | +11.6% | 1 | - | $1,131 | $230,524 | 14 | Distribution Company | false | false |
| 37 | 40 | Scoop | $1,049 | +198% | 5 | +3 | $209 | $388,346 | 12 | CDI Films | false | false |
| 38 | 30 | Ese mismo loco afán | $1,010 | -11% | 5 | - | $202 | $2,489 | 2 | N/A | false | false |
| 39 | 48 | Pathfinder | $899 | +1,854.3% | 6 | +5 | $149 | $197,279 | 12 | 20th Century Fox International | false | false |
| 40 | 42 | Epic Movie | $823 | +514.2% | 7 | +6 | $117 | $205,973 | 11 | 20th Century Fox International | false | false |
| 41 | 41 | TMNT | $815 | +317.9% | 11 | +8 | $74 | $311,084 | 10 | Distribution Company | false | false |
| 42 | 38 | Wild Hogs | $763 | +102.9% | 4 | - | $190 | $314,813 | 9 | Buena Vista International | false | false |
| 43 | 39 | 7 Years | $432 | +22.4% | 1 | -1 | $432 | $48,878 | 7 | Impacto Cine | false | false |
| 44 | 46 | Hoodwinked! | $416 | +540% | 3 | +1 | $138 | $827,138 | 18 | Alfa Films | false | false |
| 45 | 43 | The Queen | $341 | +207.2% | 2 | +1 | $170 | $848,709 | 16 | Distribution Company | false | false |
| 46 | 44 | The Education of Fairies | $340 | +273.6% | 2 | +1 | $170 | $86,815 | 11 | Buena Vista International | false | false |
| 47 | 34 | Music and Lyrics | $309 | -58.6% | 5 | -2 | $61 | $837,285 | 13 | Warner Bros. | false | false |
| 48 | 37 | Shooter | $246 | -52.3% | 2 | - | $123 | $255,934 | 10 | United International Pictures | false | false |
| 49 | 25 | Tres de corazones | $215 | -88.8% | 2 | -5 | $107 | $84,631 | 7 | Distribution Company | false | false |
| 50 | 35 | Paris, I Love You | $185 | -67.5% | 2 | -1 | $92 | $294,130 | 13 | Impacto Cine | false | false |
| 51 | 36 | Changing Times | $181 | -65.6% | 1 | -2 | $181 | $68,629 | 12 | Alfa Films | false | false |
| 52 | 47 | C.R.A.Z.Y. | $21 | -58.8% | 1 | - | $21 | $49,196 | 13 | Alfa Films | false | false |
| 53 | 45 | Arthur and the Invisibles | $16 | -82.2% | 1 | -2 | $16 | $120,590 | 10 | Alfa Films | false | false |
