| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: At World's End | $448,676 | -23.7% | 113 | -6 | $3,970 | $2,375,542 | 3 | N/A | false | false |
| 2 | - | 28 Weeks Later | $108,640 | - | 31 | - | $3,504 | $108,640 | 1 | N/A | true | false |
| 3 | 2 | Spider-Man 3 | $103,714 | -39.8% | 74 | -5 | $1,401 | $2,902,002 | 6 | N/A | false | false |
| 4 | 3 | Zodiac | $69,698 | -19.2% | 26 | +1 | $2,680 | $296,463 | 2 | N/A | false | false |
| 5 | 4 | Mr. Bean's Holiday | $58,391 | -18.7% | 26 | -50 | $2,245 | $421,099 | 4 | N/A | false | false |
| 6 | 5 | 13 segundos | $57,265 | -8.7% | 29 | +3 | $1,974 | $1,069,363 | 8 | N/A | false | false |
| 7 | 7 | Perfume: The Story of a Murderer | $29,135 | -19.2% | 19 | -1 | $1,533 | $318,602 | 5 | N/A | false | false |
| 8 | 6 | Epic Movie | $27,362 | -43.7% | 24 | +1 | $1,140 | $530,319 | 5 | N/A | false | false |
| 9 | 8 | A Virgin Grandmother | $25,155 | -16.9% | 15 | -1 | $1,677 | $1,044,457 | 15 | N/A | false | false |
| 10 | - | Hard Candy | $22,078 | - | 10 | - | $2,207 | $27,018 | 1 | N/A | true | false |
| 11 | - | Russian Dolls | $15,486 | - | 6 | - | $2,581 | $27,829 | 1 | N/A | true | false |
| 12 | 9 | Cry Wolf | $13,954 | -40% | 14 | -3 | $996 | $206,897 | 4 | N/A | false | false |
| 13 | 10 | Wild Hogs | $13,376 | -33.4% | 14 | -5 | $955 | $977,621 | 8 | N/A | false | false |
| 14 | 11 | Cake | $6,578 | -45.8% | 7 | -1 | $939 | $79,275 | 5 | N/A | false | false |
| 15 | 13 | Keeping Mum | $4,079 | -18.4% | 5 | - | $815 | $105,447 | 6 | N/A | false | false |
| 16 | 14 | Curse of the Golden Flower | $3,525 | -28.4% | 3 | -2 | $1,175 | $109,580 | 7 | N/A | false | false |
