| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Shrek the Third | $5,116,374 | - | 575 | - | $8,898 | $5,982,719 | 1 | N/A | true | false |
| 2 | 1 | Pirates of the Caribbean: At World's End | $752,487 | -62.1% | 582 | -150 | $1,292 | $15,033,700 | 4 | N/A | false | false |
| 3 | 3 | Trust the Man | $202,711 | -46.4% | 114 | -2 | $1,778 | $890,756 | 2 | N/A | false | false |
| 4 | 5 | Zodiac | $143,254 | -41.1% | 60 | - | $2,387 | $1,040,635 | 3 | N/A | false | false |
| 5 | 4 | Premonition | $127,811 | -53.6% | 114 | -9 | $1,121 | $1,199,309 | 3 | N/A | false | false |
| 6 | 2 | Spider-Man 3 | $122,551 | -76.9% | 367 | -141 | $333 | $24,033,695 | 7 | N/A | false | false |
| 7 | 6 | Fracture | $105,567 | -44% | 82 | -2 | $1,287 | $2,376,612 | 6 | N/A | false | false |
| 8 | 7 | Not by Chance | $70,293 | -53% | 59 | -2 | $1,191 | $326,625 | 2 | N/A | false | false |
| 9 | 8 | Orchestra Seats | $25,558 | -23.5% | 11 | -1 | $2,323 | $194,857 | 6 | N/A | false | false |
| 10 | 9 | Inesquecível | $6,011 | -79.8% | 18 | -35 | $333 | $202,405 | 3 | N/A | false | false |
| 11 | 10 | 28 Weeks Later | $5,689 | -78.6% | 29 | -36 | $196 | $151,849 | 3 | N/A | false | false |
| 12 | 11 | Meet the Robinsons | $5,064 | -75.2% | 33 | -13 | $153 | $3,066,138 | 11 | N/A | false | false |
| 13 | 12 | Because I Said So | $4,945 | -69.8% | 23 | -17 | $215 | $1,421,246 | 8 | N/A | false | false |
| 14 | 19 | Breaking and Entering | $2,446 | -15.7% | 3 | - | $815 | $76,756 | 6 | N/A | false | false |
| 15 | - | Primeval | $2,025 | - | 4 | - | $506 | $100,804 | 8 | N/A | false | false |
| 16 | 13 | Alpha Dog | $1,645 | -88% | 8 | -10 | $205 | $316,717 | 5 | N/A | false | false |
| 17 | 17 | Marie Antoinette | $1,492 | -60.9% | 9 | -2 | $165 | $878,677 | 14 | N/A | false | false |
| 18 | 18 | Wild Hogs | $657 | -79.2% | 7 | -10 | $93 | $1,469,326 | 9 | N/A | false | false |
| 19 | 21 | Perfect Stranger | $610 | -56.9% | 7 | -1 | $87 | $2,208,194 | 10 | N/A | false | false |
| 20 | 20 | Turma da Mônica em Uma Aventura no Tempo | $603 | -68.5% | 8 | +1 | $75 | $1,984,991 | 18 | N/A | false | false |
| 21 | 23 | Caixa Dois | $235 | -56.6% | 3 | - | $78 | $1,105,945 | 11 | N/A | false | false |
