| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Evan Almighty | $176,602 | - | 71 | - | $2,487 | $176,602 | 1 | United International Pictures | true | false |
| 2 | 1 | The Bourne Ultimatum | $157,962 | -25.4% | 77 | - | $2,051 | $998,243 | 3 | United International Pictures | false | false |
| 3 | 2 | Hairspray | $145,142 | -29.7% | 55 | - | $2,638 | $420,671 | 2 | NuMetro Distribution | false | false |
| 4 | 5 | License to Wed | $53,178 | -12.4% | 51 | +1 | $1,042 | $596,529 | 4 | Warner Bros. | false | false |
| 5 | 3 | The Simpsons Movie | $49,997 | -25.4% | 67 | -2 | $746 | $1,042,803 | 5 | 20th Century Fox International | false | false |
| 6 | 4 | Transformers | $47,851 | -24.3% | 67 | -10 | $714 | $1,404,431 | 6 | United International Pictures | false | false |
| 7 | 6 | Are We Done Yet? | $39,391 | -31.5% | 31 | - | $1,270 | $115,911 | 2 | Sony Pictures Releasing | false | false |
| 8 | 7 | Harry Potter and the Order of the Phoenix | $18,936 | -38.3% | 39 | -21 | $485 | $1,937,098 | 7 | Warner Bros. | false | false |
| 9 | - | Waitress | $17,333 | - | 12 | - | $1,444 | $17,333 | 1 | 20th Century Fox International | true | false |
| 10 | 9 | Live Free or Die Hard | $16,477 | -28.4% | 29 | -15 | $568 | $1,389,075 | 8 | 20th Century Fox International | false | false |
| 11 | 8 | Becoming Jane | $15,655 | -40.3% | 25 | - | $626 | $142,615 | 3 | Ster-Kinekor Pictures | false | false |
| 12 | - | Half Nelson | $13,499 | - | 10 | - | $1,349 | $13,499 | 1 | Ster-Kinekor Pictures | true | false |
| 13 | 11 | Mr. Brooks | $12,624 | -28.6% | 24 | -5 | $526 | $187,351 | 4 | NuMetro Distribution | false | false |
| 14 | 10 | Shrek the Third | $11,068 | -37.6% | 30 | -18 | $368 | $3,198,160 | 9 | United International Pictures | false | false |
| 15 | 12 | Vacancy | $8,987 | -15% | 18 | -5 | $499 | $131,152 | 4 | Sony Pictures Releasing | false | false |
| 16 | 13 | Black Book | $6,880 | -20.5% | 5 | - | $1,376 | $19,843 | 2 | NuMetro Distribution | false | false |
| 17 | 14 | Sivaji | $5,316 | -28.7% | 4 | - | $1,329 | $95,076 | 5 | Ster-Kinekor Pictures | false | false |
| 18 | 15 | Stomp the Yard | $4,280 | -26.8% | 12 | -2 | $356 | $437,504 | 11 | Sony Pictures Releasing | false | false |
| 19 | 16 | Curse of the Golden Flower | $3,410 | -20% | 7 | -2 | $487 | $43,040 | 4 | United International Pictures | false | false |
| 20 | 17 | Pan's Labyrinth | $3,017 | -15.7% | 6 | -1 | $502 | $130,566 | 8 | United International Pictures | false | false |
| 21 | 18 | Black Snake Moan | $2,192 | -26.7% | 5 | -5 | $438 | $16,530 | 3 | United International Pictures | false | false |
| 22 | 20 | Catch and Release | $1,988 | -2.8% | 4 | - | $497 | $38,543 | 5 | Sony Pictures Releasing | false | false |
| 23 | 21 | Perfect Stranger | $1,477 | +34.2% | 2 | - | $738 | $648,705 | 19 | Sony Pictures Releasing | false | false |
| 24 | 22 | Hostel: Part II | $1,471 | +35.3% | 4 | +1 | $367 | $52,709 | 7 | Sony Pictures Releasing | false | false |
| 25 | 23 | Reign Over Me | $850 | +16.9% | 4 | +2 | $212 | $33,520 | 7 | Sony Pictures Releasing | false | false |
