| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Knocked Up | $27,548 | - | 3 | - | $9,182 | $27,548 | 1 | N/A | true | false |
| 2 | 1 | Rush Hour 3 | $21,196 | -39.5% | 3 | - | $7,065 | $73,731 | 2 | N/A | false | false |
| 3 | 2 | Ratatouille | $10,163 | -7.4% | 7 | - | $1,451 | $294,459 | 7 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | Transformers | $6,939 | -26.2% | 5 | - | $1,387 | $133,944 | 4 | N/A | false | false |
| 5 | 4 | War | $6,702 | -22.7% | 1 | - | $6,702 | $49,909 | 3 | N/A | false | false |
| 6 | 7 | I Now Pronounce You Chuck & Larry | $6,496 | +4.1% | 2 | - | $3,248 | $90,007 | 5 | N/A | false | false |
| 7 | 5 | Skinwalkers | $6,380 | -7.6% | 1 | - | $6,380 | $18,550 | 2 | N/A | false | false |
| 8 | 8 | Fracture | $4,647 | -22.1% | 1 | - | $4,647 | $69,531 | 5 | N/A | false | false |
| 9 | 9 | The Bourne Ultimatum | $4,622 | -17.2% | 2 | - | $2,311 | $125,838 | 6 | N/A | false | false |
| 10 | 6 | Evening | $4,313 | -36.8% | 1 | - | $4,313 | $16,495 | 2 | N/A | false | false |
| 11 | - | The Call of Wild | $3,375 | - | 1 | - | $3,375 | $3,375 | 1 | N/A | true | false |
| 12 | 11 | The Simpsons Movie | $2,633 | -11% | 5 | - | $526 | $257,408 | 8 | N/A | false | false |
| 13 | 10 | Hairspray | $1,616 | -48.7% | 1 | - | $1,616 | $36,376 | 4 | N/A | false | false |
| 14 | 12 | Harry Potter and the Order of the Phoenix | $1,579 | -45.5% | 5 | - | $315 | $321,204 | 10 | N/A | false | false |
| 15 | 13 | Shrek the Third | $1,038 | -29.4% | 6 | - | $173 | $392,870 | 15 | Universal Pictures International (UPI) | false | false |
| 16 | 14 | Pirates of the Caribbean: At World's End | $892 | -16.5% | 6 | - | $148 | $462,651 | 17 | N/A | false | false |
