| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ratatouille | $298,140 | - | 40 | - | $7,453 | $298,149 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Rush Hour 3 | $133,780 | +0.9% | 70 | -1 | $1,911 | $1,062,971 | 4 | NuMetro Distribution | false | false |
| 3 | 2 | No Reservations | $66,919 | -6.2% | 46 | -1 | $1,454 | $334,462 | 3 | Warner Bros. | false | false |
| 4 | - | Bratz | $57,367 | - | 37 | - | $1,550 | $57,367 | 1 | NuMetro Distribution | true | false |
| 5 | 3 | I Now Pronounce You Chuck & Larry | $54,162 | -22.4% | 59 | -3 | $918 | $289,318 | 3 | United International Pictures | false | false |
| 6 | - | Poena Is Koning | $52,585 | - | 47 | - | $1,118 | $52,585 | 1 | Ster-Kinekor Pictures | true | false |
| 7 | - | Disturbia | $49,651 | - | 29 | - | $1,712 | $49,651 | 1 | United International Pictures | true | false |
| 8 | 4 | Hairspray | $42,608 | -15.6% | 53 | -1 | $803 | $795,027 | 6 | NuMetro Distribution | false | false |
| 9 | 7 | The Last Legion | $20,485 | -29.4% | 31 | - | $660 | $66,267 | 2 | NuMetro Distribution | false | false |
| 10 | 9 | One Night with the King | $17,447 | -5.8% | 10 | - | $1,744 | $47,780 | 2 | Ster-Kinekor Pictures | false | false |
| 11 | 8 | Nancy Drew | $12,210 | -53.3% | 31 | +1 | $393 | $45,807 | 2 | Warner Bros. | false | false |
| 12 | 6 | The Bourne Ultimatum | $11,784 | -70.4% | 36 | -18 | $327 | $1,423,160 | 7 | United International Pictures | false | false |
| 13 | 10 | Are We Done Yet? | $11,661 | -16.5% | 19 | -4 | $613 | $224,415 | 6 | Sony Pictures Releasing | false | false |
| 14 | 5 | Evan Almighty | $8,991 | -81.6% | 44 | -19 | $204 | $545,870 | 5 | United International Pictures | false | false |
| 15 | 13 | The Lives of Others | $7,640 | +0.8% | 4 | - | $1,910 | $32,450 | 3 | Ster-Kinekor Pictures | false | false |
| 16 | 11 | License to Wed | $6,436 | -47.9% | 15 | -14 | $429 | $728,565 | 8 | Warner Bros. | false | false |
| 17 | - | As It Is in Heaven | $5,090 | - | 4 | - | $1,272 | $150,933 | 22 | Ster-Kinekor Pictures | false | false |
| 18 | - | Footskating 101 - The Movie | $4,976 | - | 25 | - | $199 | $23,091 | 2 | United International Pictures | false | false |
| 19 | - | Waitress | $4,340 | - | 9 | - | $482 | $61,099 | 5 | 20th Century Fox International | false | false |
| 20 | 16 | Becoming Jane | $4,001 | -6.6% | 7 | -4 | $571 | $194,679 | 7 | Ster-Kinekor Pictures | false | false |
| 21 | 17 | Half Nelson | $3,601 | -10% | 6 | -2 | $600 | $52,743 | 5 | Ster-Kinekor Pictures | false | false |
| 22 | 18 | Transformers | $985 | -71.5% | 5 | -7 | $197 | $1,447,876 | 10 | United International Pictures | false | false |
| 23 | 21 | Catch and Release | $691 | -36% | 2 | -2 | $345 | $48,041 | 9 | Sony Pictures Releasing | false | false |
| 24 | 22 | Vacancy | $484 | -26.3% | 2 | -2 | $242 | $150,601 | 8 | Sony Pictures Releasing | false | false |
| 25 | 26 | Curse of the Golden Flower | $441 | -16.6% | 3 | -1 | $147 | $54,781 | 8 | United International Pictures | false | false |
| 26 | 20 | Stomp the Yard | $440 | -69% | 2 | -3 | $220 | $448,218 | 15 | Sony Pictures Releasing | false | false |
| 27 | 27 | Reign Over Me | $426 | +10.1% | 1 | - | $426 | $36,755 | 11 | Sony Pictures Releasing | false | false |
| 28 | 25 | Black Snake Moan | $164 | -70.7% | 1 | -3 | $164 | $23,279 | 7 | United International Pictures | false | false |
