| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | National Treasure: Book of Secrets | $193,102 | - | 61 | - | $3,165 | $200,931 | 1 | N/A | true | false |
| 2 | - | Enchanted | $154,392 | - | 60 | - | $2,573 | $1,348,123 | 3 | N/A | false | false |
| 3 | - | Alvin and the Chipmunks | $113,495 | - | 45 | - | $2,522 | $113,495 | 1 | N/A | true | false |
| 4 | - | Puras joyitas | $77,370 | - | 30 | - | $2,579 | $302,578 | 2 | N/A | false | false |
| 5 | - | Fred Claus | $77,237 | - | 51 | - | $1,514 | $389,149 | 2 | N/A | false | false |
| 6 | - | The Heartbreak Kid | $49,455 | - | 39 | - | $1,268 | $522,503 | 3 | N/A | false | false |
| 7 | - | The Golden Compass | $26,203 | - | 24 | - | $1,091 | $258,666 | 3 | N/A | false | false |
| 8 | - | The Night Listener | $14,036 | - | 8 | - | $1,754 | $302,251 | 7 | N/A | false | false |
| 9 | - | The Queen | $7,302 | - | 5 | - | $1,460 | $43,853 | 5 | N/A | false | false |
| 10 | - | Ni tan largos... ni tan cortos | $2,780 | - | 6 | - | $463 | $340,406 | 7 | N/A | false | false |
| 11 | - | Beowulf | $1,193 | - | 7 | - | $170 | $739,970 | 5 | N/A | false | false |
| 12 | - | The Invasion | $1,107 | - | 2 | - | $553 | $238,314 | 4 | N/A | false | false |
| 13 | - | Superbad | $1,077 | - | 3 | - | $359 | $245,106 | 4 | N/A | false | false |
| 14 | - | Knocked Up | $929 | - | 3 | - | $309 | $448,666 | 6 | N/A | false | false |
| 15 | - | The Seeker: The Dark Is Rising | $707 | - | 5 | - | $141 | $937,911 | 9 | N/A | false | false |
