| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Natale in crociera | $4,650,023 | +4.5% | 575 | -6 | $8,086 | $27,591,552 | 3 | Filmauro | false | false |
| 2 | 2 | A Beautiful Wife | $4,336,113 | +33.8% | 546 | +52 | $7,941 | $21,001,228 | 3 | Medusa Distribuzione | false | false |
| 3 | 3 | National Treasure: Book of Secrets | $2,361,753 | +36.7% | 334 | +37 | $7,071 | $7,354,973 | 2 | Walt Disney Pictures | false | false |
| 4 | 4 | The Golden Compass | $1,972,039 | +27.5% | 337 | -39 | $5,851 | $9,642,106 | 3 | 01 Distribution | false | false |
| 5 | 5 | Bee Movie | $1,795,654 | +68.8% | 368 | +17 | $4,879 | $5,283,972 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 6 | Lions for Lambs | $1,371,721 | +97.5% | 166 | +31 | $8,263 | $3,582,601 | 2 | 20th Century Fox International | false | false |
| 7 | 7 | Love in the Time of Cholera | $905,984 | +61.4% | 193 | +16 | $4,694 | $2,551,026 | 2 | 01 Distribution | false | false |
| 8 | 8 | Enchanted | $825,048 | +52.6% | 228 | -11 | $3,618 | $8,324,340 | 4 | Walt Disney Pictures | false | false |
| 9 | 9 | Eastern Promises | $638,432 | +46.4% | 164 | +11 | $3,892 | $2,804,127 | 3 | Eagle Pictures | false | false |
| 10 | 10 | Irina Palm | $239,352 | +79.2% | 51 | +5 | $4,693 | $1,127,209 | 4 | Teodora Film | false | false |
| 11 | 13 | Caramel | $215,124 | +248.6% | 40 | +25 | $5,378 | $413,862 | 2 | Archibald | false | false |
| 12 | 11 | Winx Club: The Secret of the Lost Kingdom | $140,733 | +61% | 104 | -23 | $1,353 | $6,619,204 | 5 | 01 Distribution | false | false |
| 13 | 12 | The Assassination of Jesse James by the Coward Robert Ford | $122,978 | +57.5% | 83 | +6 | $1,481 | $386,894 | 2 | Warner Bros. | false | false |
| 14 | 14 | In the Valley of Elah | $76,993 | +25.4% | 24 | -2 | $3,208 | $2,088,487 | 5 | Mikado Film | false | false |
| 15 | 15 | Days of Darkness | $67,895 | +16% | 26 | -10 | $2,611 | $559,475 | 4 | BIM Distribuzione | false | false |
| 16 | 16 | Paranoid Park | $47,728 | -6.8% | 20 | -7 | $2,386 | $741,537 | 4 | Lucky Red | false | false |
| 17 | 17 | Across the Universe | $43,463 | +90.3% | 13 | +1 | $3,343 | $847,322 | 6 | Sony Pictures Releasing | false | false |
| 18 | 18 | Lezioni di cioccolato | $32,692 | +73.6% | 16 | +3 | $2,043 | $3,614,734 | 6 | Universal Pictures International (UPI) | false | false |
| 19 | 20 | Days and Clouds | $20,957 | +55.2% | 9 | -2 | $2,328 | $5,451,376 | 10 | Warner Bros. | false | false |
| 20 | 19 | Don't Waste Your Time, Johnny! | $16,241 | +13.3% | 5 | -1 | $3,248 | $422,083 | 5 | Medusa Distribuzione | false | false |
| 21 | 21 | Ratatouille | $15,081 | +14.8% | 15 | -2 | $1,005 | $25,540,293 | 11 | Walt Disney Pictures | false | false |
| 22 | 24 | August Rush | $8,521 | +75.9% | 7 | +1 | $1,217 | $1,558,481 | 5 | Medusa Distribuzione | false | false |
| 23 | 22 | Hitman | $8,396 | +11% | 4 | - | $2,099 | $1,957,891 | 4 | 20th Century Fox International | false | false |
| 24 | 25 | I Viceré | $6,276 | +60% | 5 | +2 | $1,255 | $2,323,612 | 8 | 01 Distribution | false | false |
| 25 | 23 | Conversations with My Gardener | $5,440 | +5.3% | 4 | -1 | $1,360 | $387,724 | 6 | BIM Distribuzione | false | false |
| 26 | 26 | 1408 | $5,054 | +40.6% | 2 | - | $2,527 | $5,483,665 | 6 | Lucky Red | false | false |
| 27 | 31 | The Wind Blows Round | $4,698 | +130.4% | 1 | - | $4,698 | $366,044 | 35 | Aranciafilm | false | false |
| 28 | 30 | The Edge of Heaven | $4,213 | +97.9% | 3 | +1 | $1,404 | $663,531 | 8 | BIM Distribuzione | false | false |
| 29 | 32 | Beowulf | $4,115 | +117% | 2 | +1 | $2,057 | $5,072,906 | 7 | Warner Bros. | false | false |
| 30 | 41 | Milan Palermo - The Return | $4,037 | +422.3% | 4 | +3 | $1,009 | $5,827,268 | 6 | Walt Disney Pictures | false | false |
| 31 | - | The Right Distance | $3,977 | - | 3 | - | $1,325 | $1,332,950 | 11 | 01 Distribution | false | false |
| 32 | 35 | Jellyfish | $1,757 | +58.1% | 2 | -1 | $878 | $217,669 | 7 | Sacher Distribuzione | false | false |
| 33 | 44 | The Heartbreak Kid | $1,671 | +145.7% | 2 | +1 | $835 | $8,625,041 | 8 | Universal Pictures International (UPI) | false | false |
| 34 | 28 | Elizabeth: The Golden Age | $1,534 | -41.5% | 1 | -2 | $1,534 | $6,559,875 | 10 | Universal Pictures International (UPI) | false | false |
| 35 | 27 | Come tu mi vuoi | $1,353 | -55.2% | 2 | -1 | $676 | $10,423,351 | 8 | Medusa Distribuzione | false | false |
| 36 | 47 | Fracture | $1,238 | +283.3% | 1 | - | $1,238 | $3,432,586 | 9 | Eagle Pictures | false | false |
| 37 | 39 | Civico zero | $1,049 | +10.9% | 1 | - | $1,049 | $31,551 | 6 | Istituto Luce | false | false |
| 38 | 40 | Welcome to the Roses 2007 Re-release | $1,001 | +24.3% | 1 | - | $1,001 | $357,825 | 11 | Moviemax | false | false |
| 39 | 43 | Factory Girl | $995 | +38.4% | 2 | +1 | $497 | $222,732 | 6 | Moviemax | false | false |
| 40 | 37 | Little Boy Red | $970 | -2.3% | 3 | +1 | $323 | $116,126 | 7 | N/A | false | false |
| 41 | 29 | The Romance of Astrea and Celadon | $786 | -65.3% | 1 | - | $786 | $267,745 | 18 | BIM Distribuzione | false | false |
| 42 | - | The Nanny Diaries | $712 | - | 1 | - | $712 | $582,691 | 5 | 01 Distribution | false | false |
| 43 | 36 | Matrimonio alle Bahamas | $636 | -38% | 1 | - | $636 | $14,436,260 | 7 | Medusa Distribuzione | false | false |
| 44 | - | Death at a Funeral | $586 | - | 1 | - | $586 | $3,311,989 | 15 | Mikado Film | false | false |
| 45 | 49 | A Mighty Heart | $346 | +52.4% | 1 | - | $346 | $45,168 | 7 | Universal Pictures International (UPI) | false | false |
| 46 | 48 | Regular Lovers | $125 | -45.7% | 1 | - | $125 | $114,678 | 2 | Istituto Luce | false | false |
| 47 | - | Surf's Up | $40 | - | 1 | - | $40 | $2,188,459 | 13 | Sony Pictures Releasing | false | false |
