| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | I Am Legend | $703,164 | - | 53 | - | $13,267 | $1,482,633 | 1 | N/A | true | false |
| 2 | 1 | National Treasure: Book of Secrets | $379,715 | -58.9% | 53 | +1 | $7,164 | $1,742,443 | 2 | N/A | false | false |
| 3 | 2 | Alvin and the Chipmunks | $235,296 | -43.5% | 26 | -5 | $9,049 | $1,779,215 | 3 | N/A | false | false |
| 4 | 3 | The Warlords | $120,757 | -62.3% | 29 | -9 | $4,164 | $1,448,470 | 3 | N/A | false | false |
| 5 | - | Elizabeth: The Golden Age | $42,096 | - | 9 | - | $4,677 | $58,866 | 1 | N/A | true | false |
| 6 | 4 | The Golden Compass | $25,254 | -79.4% | 19 | -17 | $1,329 | $1,966,641 | 4 | N/A | false | false |
| 7 | - | My Blueberry Nights | $25,169 | - | 4 | - | $6,292 | $25,169 | 1 | N/A | true | false |
| 8 | 9 | Lust, Caution | $19,477 | -18.1% | 5 | -1 | $3,895 | $1,091,211 | 13 | N/A | false | false |
| 9 | - | Across the Universe | $18,177 | - | 3 | - | $6,059 | $18,177 | 1 | N/A | true | false |
| 10 | 8 | Redline | $18,035 | -50% | 11 | - | $1,639 | $81,332 | 2 | N/A | false | false |
| 11 | 5 | Mr. Magorium's Wonder Emporium | $11,837 | -80.3% | 8 | -10 | $1,479 | $294,687 | 3 | N/A | false | false |
| 12 | - | Vexille | $8,877 | - | 1 | - | $8,877 | $8,877 | 1 | N/A | true | false |
| 13 | 6 | Enchanted | $8,533 | -78.6% | 7 | -13 | $1,219 | $2,057,637 | 6 | N/A | false | false |
| 14 | 10 | In the Valley of Elah | $8,301 | -46.9% | 4 | - | $2,075 | $35,367 | 2 | N/A | false | false |
| 15 | 7 | Good Luck Chuck | $5,318 | -85.5% | 2 | -6 | $2,659 | $139,783 | 3 | N/A | false | false |
| 16 | 12 | Nanking | $5,192 | -41.9% | 1 | - | $5,192 | $57,479 | 4 | N/A | false | false |
| 17 | 11 | The Heartbreak Kid | $2,721 | -81.8% | 2 | -6 | $1,360 | $311,464 | 4 | N/A | false | false |
