| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | National Treasure: Book of Secrets | $1,138,738 | - | 75 | - | $15,183 | $1,138,738 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | I Am Legend | $671,692 | -47.9% | 66 | - | $10,177 | $3,658,258 | 3 | Warner Bros. | false | false |
| 3 | 5 | Alvin and the Chipmunks | $479,344 | -8.4% | 71 | - | $6,751 | $1,324,983 | 3 | 20th Century Fox International | false | false |
| 4 | 2 | Enchanted | $467,714 | -34.8% | 91 | +1 | $5,139 | $1,997,723 | 3 | Walt Disney Pictures | false | false |
| 5 | 4 | Bee Movie | $457,847 | -25.5% | 98 | +39 | $4,671 | $2,736,797 | 4 | Universal Pictures International (UPI) | false | false |
| 6 | 3 | The Golden Compass | $390,557 | -39.3% | 105 | -45 | $3,719 | $2,913,955 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 7 | 6 | K3 en de kattenprins | $263,192 | -15.9% | 36 | +30 | $7,310 | $750,690 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 8 | - | Saw IV | $215,009 | - | 35 | - | $6,143 | $867,495 | 2 | Les Films de l'Elysée | false | false |
| 9 | 7 | Gone Baby Gone | $131,576 | -40.9% | 39 | - | $3,373 | $400,881 | 2 | Walt Disney Pictures | false | false |
| 10 | 9 | Good Luck Chuck | $113,501 | -14.8% | 11 | - | $10,318 | $373,958 | 3 | Sony Pictures Releasing | false | false |
| 11 | 8 | Elizabeth: The Golden Age | $108,645 | -40.5% | 36 | -1 | $3,017 | $828,462 | 4 | Universal Pictures International (UPI) | false | false |
| 12 | 11 | Mr. Magorium's Wonder Emporium | $60,937 | -36.3% | 29 | - | $2,101 | $176,559 | 2 | Benelux Film Distributors | false | false |
| 13 | 12 | American Gangster | $55,199 | -37.9% | 29 | -1 | $1,903 | $2,084,941 | 8 | Universal Pictures International (UPI) | false | false |
| 14 | 13 | Beowulf | $47,651 | -45.4% | 15 | -5 | $3,176 | $1,484,041 | 7 | Warner Bros. | false | false |
| 15 | 14 | Eastern Promises | $47,208 | -37.5% | 17 | -4 | $2,776 | $701,672 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 16 | 15 | Cassandra's Dream | $42,485 | -34.9% | 17 | - | $2,499 | $167,710 | 2 | Cinéart | false | false |
| 17 | 10 | Hitman | $40,404 | -60.2% | 27 | -15 | $1,496 | $962,923 | 6 | 20th Century Fox International | false | false |
| 18 | 16 | Two Worlds | $37,783 | -41.2% | 9 | -3 | $4,198 | $819,198 | 7 | Benelux Film Distributors | false | false |
| 19 | - | The Fox and the Child | $35,041 | - | 16 | - | $2,190 | $158,784 | 4 | Paradiso Entertainment | false | false |
| 20 | 17 | Missing Persons Unit | $34,200 | -45.2% | 19 | -3 | $1,800 | $1,900,998 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 21 | 19 | Surviving with Wolves | $32,116 | -31% | 25 | - | $1,284 | $528,868 | 7 | Victory Productions | false | false |
| 22 | - | The Return | $30,648 | - | 11 | - | $2,786 | $107,377 | 1 | Universal Pictures International (UPI) | true | false |
| 23 | - | My Blueberry Nights | $26,199 | - | 15 | - | $1,746 | $292,377 | 5 | Cinéart | false | false |
| 24 | 18 | Cow-Boy | $25,579 | -45.5% | 20 | -1 | $1,278 | $341,743 | 5 | Belga Films | false | false |
| 25 | - | Killer Babes | $22,441 | - | 3 | - | $7,480 | $68,955 | 3 | N/A | false | false |
| 26 | - | The Secret of the Grain | $22,311 | - | 5 | - | $4,462 | $99,837 | 4 | Alternative Films | false | false |
| 27 | - | Becoming Jane | $21,424 | - | 11 | - | $1,947 | $133,570 | 2 | A-Film Distribution | false | false |
| 28 | - | Go West: A Lucky Luke Adventure | $20,636 | - | 18 | - | $1,146 | $136,916 | 5 | Alternative Films | false | false |
| 29 | - | Big City | $18,381 | - | 21 | - | $875 | $89,022 | 3 | N/A | false | false |
| 30 | - | Underdog | $16,254 | - | 19 | - | $855 | $485,881 | 7 | Walt Disney Pictures | false | false |
| 31 | - | L'auberge rouge | $14,646 | - | 17 | - | $861 | $184,618 | 4 | Les Films de l'Elysée | false | false |
| 32 | - | The Counterfeiters | $14,646 | - | 12 | - | $1,220 | $81,522 | 3 | ABC Distribution | false | false |
| 33 | - | We Own the Night | $14,637 | - | 13 | - | $1,125 | $385,322 | 6 | Paradiso Entertainment | false | false |
| 34 | - | The Edge of Heaven | $13,482 | - | 10 | - | $1,348 | $286,951 | 8 | Cinéart | false | false |
| 35 | - | For Love and Honour | $12,683 | - | 4 | - | $3,170 | $169,753 | 4 | Maxximum Film und Kunst GmbH | false | false |
| 36 | - | Ben X | $12,084 | - | 11 | - | $1,098 | $2,262,620 | 15 | Kinepolis Film Distribution (KFD) | false | false |
| 37 | - | I'm Not There | $11,679 | - | 8 | - | $1,459 | $78,043 | 3 | Cinéart | false | false |
| 38 | - | Ratatouille | $11,426 | - | 6 | - | $1,904 | $8,898,362 | 23 | Buena Vista International | false | false |
| 39 | - | It Had to be You | $8,772 | - | 10 | - | $877 | $77,334 | 3 | Cinéart | false | false |
| 40 | - | The Kingdom | $8,718 | - | 4 | - | $2,179 | $883,481 | 10 | Universal Pictures International (UPI) | false | false |
| 41 | - | Plop en de pinguïn | $7,374 | - | 5 | - | $1,474 | $1,051,637 | 12 | Kinepolis Film Distribution (KFD) | false | false |
| 42 | - | Mr. Brooks | $7,051 | - | 1 | - | $7,051 | $597,758 | 12 | Kinepolis Film Distribution (KFD) | false | false |
| 43 | - | Silent Light | $5,678 | - | 3 | - | $1,892 | $18,807 | 5 | Benelux Film Distributors | false | false |
| 44 | - | Love Is All | $4,665 | - | 2 | - | $2,332 | $205,305 | 13 | A-Film Distribution | false | false |
| 45 | - | Surf's Up | $4,175 | - | 4 | - | $1,043 | $851,974 | 11 | Sony Pictures Releasing | false | false |
| 46 | - | Animals in Love | $4,140 | - | 16 | - | $258 | $36,202 | 3 | Les Films de l'Elysée | false | false |
| 47 | - | The Grocer's Son | $3,351 | - | 6 | - | $558 | $61,021 | 6 | Benelux Film Distributors | false | false |
| 48 | - | The Bourne Ultimatum | $2,351 | - | 2 | - | $1,175 | $3,095,753 | 17 | Universal Pictures International (UPI) | false | false |
| 49 | - | You, the Living | $1,306 | - | 3 | - | $435 | $42,863 | 7 | Benelux Film Distributors | false | false |
